Lesions of the nucleus paragigantocellularis alter ex copula penile reflexes

Lesley Marson*, Marsha S. List, Kevin E. McKenna

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

100 Scopus citations

Abstract

The effects of electrolytic lesions of the rostral nucleus paragigantocellularis (nPGi) were examined on ex copula sexual reflexes in male rats. Bilateral lesions of the nPGi significantly reduced (by 50%) the onset of the first ex copula, which usually was a glans erection. In addition, the number of dorsiflexions (flips) was significantly increased. In the anesthetized spinally intact rat the urethrogenital reflex cannot be evoked. However, after chronic bilateral lesions of the rostral nPGi, half of the rats tested displayed the urethrogenital reflex prior to section of the spinal cord. These data support a role for the rostral nPGi in the descending inhibition of male sexual reflexes.

Original languageEnglish (US)
Pages (from-to)187-192
Number of pages6
JournalBrain research
Volume592
Issue number1-2
DOIs
StatePublished - Oct 2 1992

Keywords

  • Descending inhibition
  • Erection
  • Penis
  • Sexual reflex

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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