Leukemia cutis with lymphoglandular bodies: A clue to acute lymphoblastic leukemia cutis

Cynthia Obiozor, Siddhartha Ganguly, Garth R. Fraga*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Leukemia cutis describes cutaneous lesions produced by infiltrates of leukemic cells. It usually manifests contemporaneously with the initial diagnosis of systemic leukemia, but may also precede or follow systemic leukemia. Most cases are associated with acute myeloid leukemia. Adult B-cell lymphoblastic leukemia cutis is very rare. We report a 59-year-old woman with a history of B-cell acute lymphoblastic leukemia who relapsed with aleukemic lymphoblastic leukemia cutis. Lymphoglandular bodies were conspicuous on biopsy and may serve as a morphologic clue to lymphocytic differentiation while molecular and immunophenotypic studies are pending. The patient was successfully treated with local radiation therapy and oral ponatinib.

Original languageEnglish (US)
Article number10
JournalDermatology online journal
Volume21
Issue number8
StatePublished - Aug 1 2015

ASJC Scopus subject areas

  • Dermatology

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