Leukemic urate nephropathy

Y. S. Kanwar, J. R. Manaligod

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

This report describes the electron microscopic changes observed in the kidneys of a boy of 10 with urate nephropathy, who subsequently manifested overt acute lymphatic leukemia. The tubules appear to be the primary sites of injury in renal failure and urate nephropathy associated with leukemia. Tubular injury is not always associated with precipitation and phagocytosis of crystals, except in the collecting tubules where cellular changes are invariably caused by intraluminal crystallization of urates. The electron microscopic observations in this case may apply to urate nephropathy of various causes.

Original languageEnglish (US)
Pages (from-to)467-472
Number of pages6
JournalArchives of Pathology and Laboratory Medicine
Volume99
Issue number9
StatePublished - Dec 1 1975

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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