Abstract
After five years of mild, intermittent urticaria, a man had life-threatening idiopathic anaphylactic reactions associated with transient myocardial ischemia, small bowel obstruction, and orthostatic hypotension. There was no evidence of causes for the anaphylactic reactions over a two and a half year period. The total serum IgE level was increased substantially, with sharp elevations occurring during three episodes of anaphylactic reactions. The elevation in total IgE levels, which was not associated with peripheral blood eosinophilia, is the first recognized serologic abnormality in this syndrome.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 553-556 |
| Number of pages | 4 |
| Journal | The American journal of medicine |
| Volume | 76 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1984 |
Funding
From the Section of Allergy-Immunology, Department of Medicine, Northwestern University Medical School, Chicago, Illinois. This work was supported by National Institutes of Health Grant Al 11759 and the Ernest S. Bazley Trust. Requests for reprints should be addressed to Dr. Paul A. Creenberger, 303 East Chicago Avenue, Chicago, Illinois 60611. Manuscript accepted May 9, 1983.
ASJC Scopus subject areas
- General Medicine