Light and electron microscopic localization of enkephalin and tyrosine hydroxylase in neostriatum of fetal and adult rat brain.

V. M. Pickel*, S. C. Beckley, K. K. Sumal, T. H. Joh, D. J. Reis, R. J. Miller

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

In fetal rat brain, immunocytochemical localization of tyrosine hydroxylase and methionine (Met5)-enkephalin demonstrates that dopaminergic axons labeled with the biosynthetic enzyme can be detected in th neostriatum prior to the appearance of the peptide in neuronal perikarya. The tyrosine hydroxylase-labeled axon terminals in adult neotriatum may form axodendritio synapses with neurons containing enkephalin. However the majority of the dopaminergic axon terminals lack synaptic specializations in the mature neostriatum.

Original languageEnglish (US)
Pages (from-to)97-105
Number of pages9
JournalActa histochemica. Supplementband
Volume24
StatePublished - 1981

ASJC Scopus subject areas

  • Medicine(all)

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