Light Scattering "Fingerprints" of Initial Pre-dysplastic Events in Colon Carcinogenesis

Young L. Kim; Yang Liu; Ramesh K. Wali; Hemant K. Roy; Michael J. Goldberg; Alexei K. Kromine; Kun Chen; Vadim Backman

Light Scattering "Fingerprints" of Initial Pre-dysplastic Events in Colon Carcinogenesis

Young L. Kim^*, Yang Liu, Ramesh K. Wali, Hemant K. Roy, Michael J. Goldberg, Alexei K. Kromine, Kun Chen, Vadim Backman

^*Corresponding author for this work

Biomedical Engineering

Research output: Contribution to journal › Conference article › peer-review

Abstract

We report detection of slight alterations of tissue micro-architecture by recording multi-dimensional data characterizing tissue light scattering. In the animal studies, we show that these light scattering "fingerprints" change dramatically even in the earliest pre-dysplastic stages of carcinogenesis, much earlier than currently known histological, molecular, or genetic markers.

Original language	English (US)
Pages (from-to)	1076-1079
Number of pages	4
Journal	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume	2
State	Published - 2003
Event	A New Beginning for Human Health: Proceddings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Cancun, Mexico Duration: Sep 17 2003 → Sep 21 2003

Keywords

Cancer diagnosis
Elastic light scattering
Polarization light scattering spectroscopy

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Light Scattering {"}Fingerprints{"} of Initial Pre-dysplastic Events in Colon Carcinogenesis",

abstract = "We report detection of slight alterations of tissue micro-architecture by recording multi-dimensional data characterizing tissue light scattering. In the animal studies, we show that these light scattering {"}fingerprints{"} change dramatically even in the earliest pre-dysplastic stages of carcinogenesis, much earlier than currently known histological, molecular, or genetic markers.",

keywords = "Cancer diagnosis, Elastic light scattering, Polarization light scattering spectroscopy",

author = "Kim, {Young L.} and Yang Liu and Wali, {Ramesh K.} and Roy, {Hemant K.} and Goldberg, {Michael J.} and Kromine, {Alexei K.} and Kun Chen and Vadim Backman",

note = "Copyright: Copyright 2008 Elsevier B.V., All rights reserved.; A New Beginning for Human Health: Proceddings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society ; Conference date: 17-09-2003 Through 21-09-2003",

year = "2003",

language = "English (US)",

volume = "2",

pages = "1076--1079",

journal = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",

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publisher = "Institute of Electrical and Electronics Engineers Inc.",

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T1 - Light Scattering "Fingerprints" of Initial Pre-dysplastic Events in Colon Carcinogenesis

AU - Kim, Young L.

AU - Liu, Yang

AU - Wali, Ramesh K.

AU - Roy, Hemant K.

AU - Goldberg, Michael J.

AU - Kromine, Alexei K.

AU - Chen, Kun

AU - Backman, Vadim

PY - 2003

Y1 - 2003

N2 - We report detection of slight alterations of tissue micro-architecture by recording multi-dimensional data characterizing tissue light scattering. In the animal studies, we show that these light scattering "fingerprints" change dramatically even in the earliest pre-dysplastic stages of carcinogenesis, much earlier than currently known histological, molecular, or genetic markers.

AB - We report detection of slight alterations of tissue micro-architecture by recording multi-dimensional data characterizing tissue light scattering. In the animal studies, we show that these light scattering "fingerprints" change dramatically even in the earliest pre-dysplastic stages of carcinogenesis, much earlier than currently known histological, molecular, or genetic markers.

KW - Cancer diagnosis

KW - Elastic light scattering

KW - Polarization light scattering spectroscopy

UR - http://www.scopus.com/inward/record.url?scp=1542332391&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1542332391&partnerID=8YFLogxK

M3 - Conference article

AN - SCOPUS:1542332391

SN - 1557-170X

VL - 2

SP - 1076

EP - 1079

JO - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

JF - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

T2 - A New Beginning for Human Health: Proceddings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Y2 - 17 September 2003 through 21 September 2003

ER -

Light Scattering "Fingerprints" of Initial Pre-dysplastic Events in Colon Carcinogenesis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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