Light Scattering "Fingerprints" of Initial Pre-dysplastic Events in Colon Carcinogenesis

Young L. Kim*, Yang Liu, Ramesh K. Wali, Hemant K. Roy, Michael J. Goldberg, Alexei K. Kromine, Kun Chen, Vadim Backman

*Corresponding author for this work

Research output: Contribution to journalConference article

Abstract

We report detection of slight alterations of tissue micro-architecture by recording multi-dimensional data characterizing tissue light scattering. In the animal studies, we show that these light scattering "fingerprints" change dramatically even in the earliest pre-dysplastic stages of carcinogenesis, much earlier than currently known histological, molecular, or genetic markers.

Original languageEnglish (US)
Pages (from-to)1076-1079
Number of pages4
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume2
StatePublished - Dec 1 2003
EventA New Beginning for Human Health: Proceddings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Cancun, Mexico
Duration: Sep 17 2003Sep 21 2003

Keywords

  • Cancer diagnosis
  • Elastic light scattering
  • Polarization light scattering spectroscopy

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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