Identifying which ligands might bind to a protein before crystallization trials could provide a significant saving in time and resources. LigSearch, a web server aimed at predicting ligands that might bind to and stabilize a given protein, has been developed. Using a protein sequence and/or structure, the system searches against a variety of databases, combining available knowledge, and provides a clustered and ranked output of possible ligands. LigSearch can be accessed at http://www.ebi.ac.uk/thornton-srv/databases/LigSearch.
|Original language||English (US)|
|Number of pages||8|
|Journal||Acta Crystallographica Section D: Biological Crystallography|
|State||Published - Dec 2013|
- Ligand prediction
ASJC Scopus subject areas
- Structural Biology