Abstract
Identifying which ligands might bind to a protein before crystallization trials could provide a significant saving in time and resources. LigSearch, a web server aimed at predicting ligands that might bind to and stabilize a given protein, has been developed. Using a protein sequence and/or structure, the system searches against a variety of databases, combining available knowledge, and provides a clustered and ranked output of possible ligands. LigSearch can be accessed at http://www.ebi.ac.uk/thornton-srv/databases/LigSearch.
Original language | English (US) |
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Pages (from-to) | 2395-2402 |
Number of pages | 8 |
Journal | Acta Crystallographica Section D: Biological Crystallography |
Volume | 69 |
Issue number | 12 |
DOIs | |
State | Published - Dec 2013 |
Keywords
- LigSearch
- Ligand prediction
ASJC Scopus subject areas
- Structural Biology