Limited Tissue Samples: Hematopoietic Lesions - Three Case Examples of Judicious Use of Limited Material

Amy Chadburn*, Yi Hua Chen, Ritu Nayar, April Young, Ingrid Sumpter, Christopher Lee, Manjot Gill, Juehau Gao

*Corresponding author for this work

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

In the era of smaller and smaller biopsies submitted to pathology departments for diagnosis and the advent of personalized medicine, it has become imperative to efficiently and effectively use patient material to reach individualized, actionable diagnoses. The use of fine needle aspirates and core biopsies as acceptable methods for obtaining sufficient material for hematopoietic neoplasms under nonemergent conditions is debatable. There are, however, scenarios where only limited material is obtainable due to anatomic site, size of the lesion or condition of the patient. In these types of settings, thoughtful approaches and unconventional means are often necessary to reach a diagnosis. In this article, we describe three such scenarios and the unique tactics taken in each to obtain a personalized actionable diagnosis.

Original languageEnglish (US)
Pages (from-to)71-80
Number of pages10
JournalActa Cytologica
Volume64
Issue number1-2
DOIs
StatePublished - Jan 1 2020

Keywords

  • Immunohistochemistry
  • Myeloid sarcoma
  • Ocular lymphoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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