Linear and quadratic associations of plasma oxytocin with depressive symptoms in ethnic minority women living with HIV

Julia S. Seay*, Emily Lattie, Neil Schneiderman, Michael H. Antoni, Erin M. Fekete, Armando J. Mendez, Angela Szeto, Mary Ann Fletcher

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The current study examines both linear and curvilinear relationships between oxytocin (OT) and depressive symptoms over time in ethnic minority women living with human immunodeficiency virus (HIV; WLWH). Participants were 70 WLWH aged 20-49 (86% African-American or Caribbean). OT was measured at baseline via enzyme-linked immunosorbent assay immunoassay procedures. Depressive symptoms were measured at both baseline and 10-week post-baseline via the Beck Depression Inventory-II (BDI-II). Multiple regression analyses revealed marginal linear and significant quadratic OT terms to be predictors of T2 BDI scores. Results indicate that to a point, OT may have salutary effects on depressive symptoms in ethnic minority WLWH. However, extremely high OT levels may be related to greater depressive symptoms.

Original languageEnglish (US)
Pages (from-to)70-78
Number of pages9
JournalJournal of Applied Biobehavioral Research
Volume19
Issue number1
DOIs
StatePublished - Mar 2014

ASJC Scopus subject areas

  • Cultural Studies
  • Experimental and Cognitive Psychology
  • Clinical Psychology
  • Social Sciences (miscellaneous)

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