Linkage mapping of microdissected clones from distal mouse chromosome 16

Jianjun Wei*, Stephen R. Dlouhy, Yi Wang, Jianguo Zhu, Lillian Fitzpatrick, Bernardino Ghetti, M. E. Hodes

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

A total of 38 unique segments generated by microdissection of mouse chromosome 16 (MMU16), sequence independent amplification (SIA) and cloning were sequentially mapped on the distal portion of the chromosome with two mouse backcross panels. Some reference markers from other sources were retyped in the panels and results integrated with those for our microdissected DNA segments. The clone map is most highly refined in its distal portion, which stretches from reference marker D16Mit71 to D16Mit5, and the highest density of clones is in the region defined by markers D16Mit5 and D16Mit141. This map on distal mouse chromosome 16 should be a useful tool for the mouse genome project and for studies of genes in the region.

Original languageEnglish (US)
Pages (from-to)227-232
Number of pages6
JournalSomatic Cell and Molecular Genetics
Volume22
Issue number3
DOIs
StatePublished - May 1996

ASJC Scopus subject areas

  • Genetics
  • Cell Biology

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