Lipid rafts: Membrane triage centers

Xiao Qi Wang, Amy S. Paller*

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

18 Scopus citations

Abstract

Both biochemical and live cell imaging studies suggest the existence of lipid rafts, specialized membrane microdomains that promote interaction among signaling molecules. Although their composition is still poorly understood, these highly dynamic domains are enriched in cholesterol, sphingolipids, and particular groups of proteins. The mechanism(s) by which trafficking into or out of lipid rafts affects signaling remains unclear.

Original languageEnglish (US)
Pages (from-to)951-953
Number of pages3
JournalJournal of Investigative Dermatology
Volume126
Issue number5
DOIs
StatePublished - May 2006

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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