Living related liver transplantation in children: a report of the first 58 recipients at the University of Chicago

J. B. Piper, P. F. Whitington, E. S. Woodle, K. A. Newell, E. M. Alonso, J. R. Thistlethwaite, J. B. Piper, E. S. Woodle, K. A. Newell, E. M. Alonso

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Abstract From November 1989 58 living donor liver transplants were performed in 56 children ranging in age from 1 month to 13 years. Donors were adults (> 18 years of age) with a close relationship to the recipient. ABO compatibility and normal donor health were required. Liver segments two and three were transplanted in 53 cases, and segments two, three and four in 5 cases. Actuarial patient survival at 2 years was 89%; graft survival was 76%. Six recipients died: four secondary to sepsis and two because of post‐transplant lymphoproliferative disease. The main cause of graft loss was arterial thrombosis, occurring in six patients (10%). Since refinement of the technique, there have been few donor complications, but these have included a biliary tract injury and a hepatic artery thrombosis. Both donors are well, without long‐term adverse sequelae. Overall, the outcome of living donor transplantation is excellent; morbidity has been encountered in a small number of donors.

Original languageEnglish (US)
Pages (from-to)111-113
Number of pages3
JournalTransplant International
Volume7
DOIs
StatePublished - Dec 1994

Keywords

  • Living donor liver
  • transplantation Children

ASJC Scopus subject areas

  • Transplantation

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