Localization of lamins in mammalian spermatozoa

R. D. Goldman, B. Baccetti*, G. Collodel, L. Gambera, E. Moretti, P. Piomboni

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Little information is available concerning lamins in the nucleus of germinal cells. In this paper we briefly describe and compare the organization of A- and B-type lamins in several mammalian spermatozoa. Nuclear lamin B is localized primarily in the postacrosomal sheath of human, bull and rabbit spermatozoa; lamin A/C is a major component of the equatorial segment in most of mammalian sperm, with the exception of rodents. In mouse sperm, devoid of equatorial segment, only lamin B appears to be expressed. The same happens in human pathological spermatozoa in which the equatorial segment is altered or absent.

Original languageEnglish (US)
Pages (from-to)573-580
Number of pages8
JournalJournal of Submicroscopic Cytology and Pathology
Volume30
Issue number4
StatePublished - Oct 1998

Keywords

  • Electron microscopy
  • Immunocytochemistry
  • Lamin
  • Mammalian spermatozoa

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Cell Biology

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