Localization of the gene for 4 hereditary multiple exostoses families

Yong Tang*, Jia Hui Xia, Jiang Nan Zhou, He Jun Li, Da Ping Wang, He Ping Dai, Zhi Gao Long, Bei Sha Tang, Lei Huang, Han Xiang Deng

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

We investigated 11 families with hereditary multiple exostoses (EXT) by linkage analysis using 8 short-tandem-repeat (CA) n polymorphic markers on chromosomes 8, 11 and 19. The Lod score in four families indicated that the gene responsible for EXT is located in the pericentromeric region of chromosome 11.

Original languageEnglish (US)
Pages (from-to)5-7
Number of pages3
JournalActa Genetica Sinica
Volume25
Issue number1
StatePublished - Dec 1 1998

Keywords

  • EXT gene
  • Hereditary multiple exostoses
  • Linkage analysis
  • Short-tandem-repeat

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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  • Cite this

    Tang, Y., Xia, J. H., Zhou, J. N., Li, H. J., Wang, D. P., Dai, H. P., Long, Z. G., Tang, B. S., Huang, L., & Deng, H. X. (1998). Localization of the gene for 4 hereditary multiple exostoses families. Acta Genetica Sinica, 25(1), 5-7.