Location Matters: Synaptotagmin Helps Place Vesicles Near Calcium Channels

Benjamin D. McNeil, Ling Gang Wu*

*Corresponding author for this work

Research output: Contribution to journalShort survey

3 Scopus citations

Abstract

Positioning releasable vesicles near voltage-gated calcium channels may ensure transmitter release upon calcium influx. Disruption of vesicle positioning may underlie short-term synaptic depression. However, how this positioning is achieved is unclear. In this issue of Neuron, Young and Neher find that synaptotagmin 2 helps to align readily releasable vesicles near calcium channels at nerve terminals.

Original languageEnglish (US)
Pages (from-to)419-421
Number of pages3
JournalNeuron
Volume63
Issue number4
DOIs
StatePublished - Aug 27 2009
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

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