Loneliness, social network size, and immune response to influenza vaccination in college freshmen

Sarah D. Pressman, Sheldon Cohen, Anita Barkin, Gregory E. Miller, Bruce S. Rabin, John J. Treanor

Research output: Contribution to journalArticle

  • 224 Citations

Abstract

Antibody response to the influenza immunization was investigated in 83 1st-semester healthy university freshmen. Elevated levels of loneliness throughout the semester and small social networks were independently associated with poorer antibody response to 1 component of the vaccine. Those with both high levels of loneliness and a small social network had the lowest antibody response. Loneliness was also associated with greater psychological stress and negative affect, less positive affect, poorer sleep efficiency and quality, and elevations in circulating levels of cortisol. However, only the stress data were consistent with mediation of the loneliness-antibody response relation. None of these variables were associated with social network size, and hence none were potential mediators of the relation between network size and immunization response.

LanguageEnglish (US)
Pages297-306
Number of pages10
JournalHealth Psychology
Volume24
Issue number3
DOIs
StatePublished - May 1 2005

Fingerprint

Loneliness
Social Support
Human Influenza
Antibody Formation
Vaccination
Immunization
Psychological Stress
Hydrocortisone
Sleep
Vaccines

Keywords

  • Loneliness
  • Sleep
  • Social network size
  • Stress
  • Vaccination

ASJC Scopus subject areas

  • Applied Psychology
  • Psychiatry and Mental health

Cite this

Pressman, Sarah D. ; Cohen, Sheldon ; Barkin, Anita ; Miller, Gregory E. ; Rabin, Bruce S. ; Treanor, John J. / Loneliness, social network size, and immune response to influenza vaccination in college freshmen. In: Health Psychology. 2005 ; Vol. 24, No. 3. pp. 297-306.
@article{422ec211262f45aa95cfde8289ea5e1d,
title = "Loneliness, social network size, and immune response to influenza vaccination in college freshmen",
abstract = "Antibody response to the influenza immunization was investigated in 83 1st-semester healthy university freshmen. Elevated levels of loneliness throughout the semester and small social networks were independently associated with poorer antibody response to 1 component of the vaccine. Those with both high levels of loneliness and a small social network had the lowest antibody response. Loneliness was also associated with greater psychological stress and negative affect, less positive affect, poorer sleep efficiency and quality, and elevations in circulating levels of cortisol. However, only the stress data were consistent with mediation of the loneliness-antibody response relation. None of these variables were associated with social network size, and hence none were potential mediators of the relation between network size and immunization response.",
keywords = "Loneliness, Sleep, Social network size, Stress, Vaccination",
author = "Pressman, {Sarah D.} and Sheldon Cohen and Anita Barkin and Miller, {Gregory E.} and Rabin, {Bruce S.} and Treanor, {John J.}",
year = "2005",
month = "5",
day = "1",
doi = "10.1037/0278-6133.24.3.297",
language = "English (US)",
volume = "24",
pages = "297--306",
journal = "Health Psychology",
issn = "0278-6133",
publisher = "American Psychological Association Inc.",
number = "3",

}

Loneliness, social network size, and immune response to influenza vaccination in college freshmen. / Pressman, Sarah D.; Cohen, Sheldon; Barkin, Anita; Miller, Gregory E.; Rabin, Bruce S.; Treanor, John J.

In: Health Psychology, Vol. 24, No. 3, 01.05.2005, p. 297-306.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Loneliness, social network size, and immune response to influenza vaccination in college freshmen

AU - Pressman, Sarah D.

AU - Cohen, Sheldon

AU - Barkin, Anita

AU - Miller, Gregory E.

AU - Rabin, Bruce S.

AU - Treanor, John J.

PY - 2005/5/1

Y1 - 2005/5/1

N2 - Antibody response to the influenza immunization was investigated in 83 1st-semester healthy university freshmen. Elevated levels of loneliness throughout the semester and small social networks were independently associated with poorer antibody response to 1 component of the vaccine. Those with both high levels of loneliness and a small social network had the lowest antibody response. Loneliness was also associated with greater psychological stress and negative affect, less positive affect, poorer sleep efficiency and quality, and elevations in circulating levels of cortisol. However, only the stress data were consistent with mediation of the loneliness-antibody response relation. None of these variables were associated with social network size, and hence none were potential mediators of the relation between network size and immunization response.

AB - Antibody response to the influenza immunization was investigated in 83 1st-semester healthy university freshmen. Elevated levels of loneliness throughout the semester and small social networks were independently associated with poorer antibody response to 1 component of the vaccine. Those with both high levels of loneliness and a small social network had the lowest antibody response. Loneliness was also associated with greater psychological stress and negative affect, less positive affect, poorer sleep efficiency and quality, and elevations in circulating levels of cortisol. However, only the stress data were consistent with mediation of the loneliness-antibody response relation. None of these variables were associated with social network size, and hence none were potential mediators of the relation between network size and immunization response.

KW - Loneliness

KW - Sleep

KW - Social network size

KW - Stress

KW - Vaccination

UR - http://www.scopus.com/inward/record.url?scp=18744387715&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=18744387715&partnerID=8YFLogxK

U2 - 10.1037/0278-6133.24.3.297

DO - 10.1037/0278-6133.24.3.297

M3 - Article

VL - 24

SP - 297

EP - 306

JO - Health Psychology

T2 - Health Psychology

JF - Health Psychology

SN - 0278-6133

IS - 3

ER -