Long-range electron transfer through DNA films

Shana O. Kelley; Nicole M. Jackson; Michael G. Hill; Jacqueline K. Barton

doi:10.1002/(SICI)1521-3773(19990401)38:7<941::AID-ANIE941>3.0.CO;2-7

Long-range electron transfer through DNA films

Shana O. Kelley, Nicole M. Jackson, Michael G. Hill^*, Jacqueline K. Barton

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

417 Scopus citations

Abstract

Regardless of its position within the DNA film, cross-linked daunomycin (DM) is efficiently reduced electrochemically, indicating that the electron transfer exhibits a shallow distance dependence. Upon the introduction of an intervening cytosine-adenine (CA) mismatch, the electrochemical response is dramatically attenuated (shown schematically). Therefore, the DNA double helix can facilitate long-range electron transfer, but only in the presence of a well-stacked pathway.

Original language	English (US)
Pages (from-to)	941-945
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	38
Issue number	7
DOIs	https://doi.org/10.1002/(SICI)1521-3773(19990401)38:7<941::AID-ANIE941>3.0.CO;2-7
State	Published - Apr 1 1999
Externally published	Yes

Keywords

Biosensors
Cyclic voltammetry
DNA structures
Electron transfer
Monolayers
Thin films

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/(SICI)1521-3773(19990401)38:7<941::AID-ANIE941>3.0.CO;2-7

Cite this

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title = "Long-range electron transfer through DNA films",

abstract = "Regardless of its position within the DNA film, cross-linked daunomycin (DM) is efficiently reduced electrochemically, indicating that the electron transfer exhibits a shallow distance dependence. Upon the introduction of an intervening cytosine-adenine (CA) mismatch, the electrochemical response is dramatically attenuated (shown schematically). Therefore, the DNA double helix can facilitate long-range electron transfer, but only in the presence of a well-stacked pathway.",

keywords = "Biosensors, Cyclic voltammetry, DNA structures, Electron transfer, Monolayers, Thin films",

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T1 - Long-range electron transfer through DNA films

AU - Kelley, Shana O.

AU - Jackson, Nicole M.

AU - Hill, Michael G.

AU - Barton, Jacqueline K.

PY - 1999/4/1

Y1 - 1999/4/1

N2 - Regardless of its position within the DNA film, cross-linked daunomycin (DM) is efficiently reduced electrochemically, indicating that the electron transfer exhibits a shallow distance dependence. Upon the introduction of an intervening cytosine-adenine (CA) mismatch, the electrochemical response is dramatically attenuated (shown schematically). Therefore, the DNA double helix can facilitate long-range electron transfer, but only in the presence of a well-stacked pathway.

AB - Regardless of its position within the DNA film, cross-linked daunomycin (DM) is efficiently reduced electrochemically, indicating that the electron transfer exhibits a shallow distance dependence. Upon the introduction of an intervening cytosine-adenine (CA) mismatch, the electrochemical response is dramatically attenuated (shown schematically). Therefore, the DNA double helix can facilitate long-range electron transfer, but only in the presence of a well-stacked pathway.

KW - Biosensors

KW - Cyclic voltammetry

KW - DNA structures

KW - Electron transfer

KW - Monolayers

KW - Thin films

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JF - Angewandte Chemie - International Edition

IS - 7

ER -

Long-range electron transfer through DNA films

Abstract

Keywords

ASJC Scopus subject areas

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