Long-term control after resection and gamma knife surgery of an intracranial clear cell meningioma. Case report

Edward S. Ahn, Lawrence S. Chin*, Kymberly A. Gyure, Richard S. Hudes, John Ragheb, Arthur J. DiPatri

*Corresponding author for this work

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Clear cell meningioma (CCM) is a rare variant of meningioma characterized by sheets of polygonal cells with clear cytoplasm, a feature attributable to its high glycogen content. Authors have described its propensity to recur and metastasize despite its benign pathological characteristics. Clinical response to radiation in these reports has varied. The authors present the case of a 7-year-old girl with a large petroclival CCM who underwent a staged subtotal resection and subsequent gamma knife surgery (GKS). Initially, the residual tumor decreased in size, but 6 years later, it had regrown (9 mm in size). A second GKS treatment was performed and the mass completely regressed without further complication. The findings in this case suggest that GKS is a safe and effective adjunct for residual and recurrent CCM after resection. The delayed recurrence also emphasizes the importance of undertaking close follow-up examination after treating this potentially aggressive variant of meningioma.

Original languageEnglish (US)
Pages (from-to)303-306
Number of pages4
JournalJournal of neurosurgery
Volume102 PEDIATRICS
Issue numberSUPPL. 3
StatePublished - Apr 1 2005

Keywords

  • Clear cell meningioma
  • Gamma knife surgery
  • Pediatric neurosurgery
  • Stereotactic radiosurgery

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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    Ahn, E. S., Chin, L. S., Gyure, K. A., Hudes, R. S., Ragheb, J., & DiPatri, A. J. (2005). Long-term control after resection and gamma knife surgery of an intracranial clear cell meningioma. Case report. Journal of neurosurgery, 102 PEDIATRICS(SUPPL. 3), 303-306.