TY - JOUR
T1 - Long-term course of pediatric obsessive-compulsive disorder
T2 - 3 years of prospective follow-up
AU - Mancebo, Maria C.
AU - Boisseau, Christina Lynn
AU - Garnaat, Sarah L.
AU - Eisen, Jane L.
AU - Greenberg, Benjamin D.
AU - Sibrava, Nicholas J.
AU - Stout, Robert L.
AU - Rasmussen, Steven A.
N1 - Publisher Copyright:
© 2014 Elsevier Inc. All rights reserved.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - Objective This study assesses the long-term course of treatment-seeking youth with a primary diagnosis of DSM-IV OCD.Method Sixty youth and their parents completed intake interviews and annual follow-up interviews for 3 years using the youth version of the Longitudinal Interval Follow-up Evaluation (Y-LIFE) and Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS). Remission was defined as no longer meeting DSM-IV criteria for OCD for 8 weeks or more, and recurrence was defined as meeting full criteria for OCD for 4 consecutive weeks after having achieved symptom remission. Remission rates for youth were compared to rates of adults participating in the same study.Results The probability of achieving partial remission of OCD was 0.53 and the probability of achieving full remission was 0.27. Among the 24 youth participants who achieved remission, 79% stayed in remission throughout the study (mean of 88 weeks of follow-up) and 21% experienced a recurrence of symptoms. Better functioning at intake and a shorter latency to initial OCD treatment were associated with faster onset of remission (P <.001).Conclusions Remission is more likely among youth versus adults with OCD. Treatment early in the course of illness and before substantial impact on functioning predicted a better course.
AB - Objective This study assesses the long-term course of treatment-seeking youth with a primary diagnosis of DSM-IV OCD.Method Sixty youth and their parents completed intake interviews and annual follow-up interviews for 3 years using the youth version of the Longitudinal Interval Follow-up Evaluation (Y-LIFE) and Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS). Remission was defined as no longer meeting DSM-IV criteria for OCD for 8 weeks or more, and recurrence was defined as meeting full criteria for OCD for 4 consecutive weeks after having achieved symptom remission. Remission rates for youth were compared to rates of adults participating in the same study.Results The probability of achieving partial remission of OCD was 0.53 and the probability of achieving full remission was 0.27. Among the 24 youth participants who achieved remission, 79% stayed in remission throughout the study (mean of 88 weeks of follow-up) and 21% experienced a recurrence of symptoms. Better functioning at intake and a shorter latency to initial OCD treatment were associated with faster onset of remission (P <.001).Conclusions Remission is more likely among youth versus adults with OCD. Treatment early in the course of illness and before substantial impact on functioning predicted a better course.
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U2 - 10.1016/j.comppsych.2014.04.010
DO - 10.1016/j.comppsych.2014.04.010
M3 - Article
C2 - 24952937
AN - SCOPUS:84907740270
SN - 0010-440X
VL - 55
SP - 1498
EP - 1504
JO - Comprehensive Psychiatry
JF - Comprehensive Psychiatry
IS - 7
ER -
