Long-term evaluation of MEK inhibitor retinal toxicity with multimodal imaging

Alan T. Sheyman; Fabio Scarinci; Amani A. Fawzi; Manjot K. Gill

doi:10.3928/23258160-20151214-12

Long-term evaluation of MEK inhibitor retinal toxicity with multimodal imaging

Alan T. Sheyman, Fabio Scarinci, Amani A. Fawzi, Manjot K. Gill^*

^*Corresponding author for this work

Ophthalmology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

MEK inhibitor chemotherapy, used in various malignancies, has been reported to be associated with serous retinal detachments. This study reports serial multimodal imaging focused primarily on infrared reflectance and spectral-domain optical coherence tomography (SD-OCT) in the monitoring of MEK inhibitor retinal toxicity. The benefit of OCT angiography in understanding the pathophysiology of MEK inhibitor toxicity is also shown.

Original language	English (US)
Pages (from-to)	76-77
Number of pages	2
Journal	Ophthalmic Surgery Lasers and Imaging Retina
Volume	47
Issue number	1
DOIs	https://doi.org/10.3928/23258160-20151214-12
State	Published - Jan 2016

ASJC Scopus subject areas

Ophthalmology
Surgery

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title = "Long-term evaluation of MEK inhibitor retinal toxicity with multimodal imaging",

abstract = "MEK inhibitor chemotherapy, used in various malignancies, has been reported to be associated with serous retinal detachments. This study reports serial multimodal imaging focused primarily on infrared reflectance and spectral-domain optical coherence tomography (SD-OCT) in the monitoring of MEK inhibitor retinal toxicity. The benefit of OCT angiography in understanding the pathophysiology of MEK inhibitor toxicity is also shown.",

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N2 - MEK inhibitor chemotherapy, used in various malignancies, has been reported to be associated with serous retinal detachments. This study reports serial multimodal imaging focused primarily on infrared reflectance and spectral-domain optical coherence tomography (SD-OCT) in the monitoring of MEK inhibitor retinal toxicity. The benefit of OCT angiography in understanding the pathophysiology of MEK inhibitor toxicity is also shown.

AB - MEK inhibitor chemotherapy, used in various malignancies, has been reported to be associated with serous retinal detachments. This study reports serial multimodal imaging focused primarily on infrared reflectance and spectral-domain optical coherence tomography (SD-OCT) in the monitoring of MEK inhibitor retinal toxicity. The benefit of OCT angiography in understanding the pathophysiology of MEK inhibitor toxicity is also shown.

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Long-term evaluation of MEK inhibitor retinal toxicity with multimodal imaging

Abstract

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