Long-term potentiation in intact infant rat hippocampus

Barbara L. Trommer; Aryeh Routtenberg

doi:10.1016/0165-3806(90)90020-Y

Long-term potentiation in intact infant rat hippocampus

Barbara L. Trommer^*, Aryeh Routtenberg

^*Corresponding author for this work

Psychology

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

In rats 14-28 days of age, high-frequency stimulation of the perforant path granule cell synapse in the dentate gyrus produced long-term potentiation of the population spike that was comparable in magnitude (150-250% of baseline) and duration (120 min) to that produced in adult animals with the same stimulation paradigm. In contrast, potentiation of the excitatory postsynaptic potential occurred inconsistently.

Original language	English (US)
Pages (from-to)	288-290
Number of pages	3
Journal	Developmental Brain Research
Volume	53
Issue number	2
DOIs	https://doi.org/10.1016/0165-3806(90)90020-Y
State	Published - May 1 1990

Keywords

Dentate gyrus
Developing nervous system
Hippocampus
Long-term potentiation

ASJC Scopus subject areas

Developmental Neuroscience
Developmental Biology

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10.1016/0165-3806(90)90020-Y

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title = "Long-term potentiation in intact infant rat hippocampus",

abstract = "In rats 14-28 days of age, high-frequency stimulation of the perforant path granule cell synapse in the dentate gyrus produced long-term potentiation of the population spike that was comparable in magnitude (150-250% of baseline) and duration (120 min) to that produced in adult animals with the same stimulation paradigm. In contrast, potentiation of the excitatory postsynaptic potential occurred inconsistently.",

keywords = "Dentate gyrus, Developing nervous system, Hippocampus, Long-term potentiation",

author = "Trommer, {Barbara L.} and Aryeh Routtenberg",

note = "Funding Information: Supported in part by generous gifts from the Arie and Ida Crown Memorial Fund to B.L.T. and by MH25281 and AFOSR 87-0042 to A.R.B.L.T. would like to thank Dr. Patricia A. Colley for demonstrating the technique of long-term potentiation in adult animals.",

year = "1990",

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doi = "10.1016/0165-3806(90)90020-Y",

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T1 - Long-term potentiation in intact infant rat hippocampus

AU - Trommer, Barbara L.

AU - Routtenberg, Aryeh

N1 - Funding Information: Supported in part by generous gifts from the Arie and Ida Crown Memorial Fund to B.L.T. and by MH25281 and AFOSR 87-0042 to A.R.B.L.T. would like to thank Dr. Patricia A. Colley for demonstrating the technique of long-term potentiation in adult animals.

PY - 1990/5/1

Y1 - 1990/5/1

N2 - In rats 14-28 days of age, high-frequency stimulation of the perforant path granule cell synapse in the dentate gyrus produced long-term potentiation of the population spike that was comparable in magnitude (150-250% of baseline) and duration (120 min) to that produced in adult animals with the same stimulation paradigm. In contrast, potentiation of the excitatory postsynaptic potential occurred inconsistently.

AB - In rats 14-28 days of age, high-frequency stimulation of the perforant path granule cell synapse in the dentate gyrus produced long-term potentiation of the population spike that was comparable in magnitude (150-250% of baseline) and duration (120 min) to that produced in adult animals with the same stimulation paradigm. In contrast, potentiation of the excitatory postsynaptic potential occurred inconsistently.

KW - Dentate gyrus

KW - Developing nervous system

KW - Hippocampus

KW - Long-term potentiation

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Long-term potentiation in intact infant rat hippocampus

Abstract

Keywords

ASJC Scopus subject areas

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