Longitudinal comparison of diffusion tensor imaging parameters and neuropsychological measures following endoscopic third ventriculostomy for hydrocephalus. Case report

Robert T. Buckley; Weihong Yuan; Francesco T. Mangano; Jannel M. Phillips; Stephanie Powell; Robert C. McKinstry; Akila Rajagopal; Blaise V. Jones; Scott Holland; David D. Limbrick

doi:10.3171/2012.2.PEDS11331

Longitudinal comparison of diffusion tensor imaging parameters and neuropsychological measures following endoscopic third ventriculostomy for hydrocephalus. Case report

Robert T. Buckley^*, Weihong Yuan, Francesco T. Mangano, Jannel M. Phillips, Stephanie Powell, Robert C. McKinstry, Akila Rajagopal, Blaise V. Jones, Scott Holland, David D. Limbrick

^*Corresponding author for this work

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

The authors report the case of a 25-month-old boy who underwent endoscopic third ventriculostomy (ETV) for hydrocephalus resulting from aqueductal stenosis. The patient's recovery was monitored longitudinally and prospectively using MR diffusion tensor imaging (DTI) and formal neuropsychological testing. Despite minimal change in ventricle size, improvement in the DTI characteristics and neurodevelopmental trajectory was observed following ETV. These data support the use of DTI as a biomarker to assess therapeutic response in children undergoing surgical treatment for hydrocephalus. In the patient featured in this report, DTI appeared to provide more information regarding postoperative neurodevelopmental outcome than ventricle size alone.

Original language	English (US)
Pages (from-to)	630-635
Number of pages	6
Journal	Journal of Neurosurgery: Pediatrics
Volume	9
Issue number	6
DOIs	https://doi.org/10.3171/2012.2.PEDS11331
State	Published - Jun 2012

Keywords

Diffusion tensor imaging
Endoscopic third ventriculostomy
Hydrocephalus
Neuropsychological outcome

ASJC Scopus subject areas

Clinical Neurology
Surgery
Pediatrics, Perinatology, and Child Health

Access to Document

10.3171/2012.2.PEDS11331

Cite this

Buckley, R. T., Yuan, W., Mangano, F. T., Phillips, J. M., Powell, S., McKinstry, R. C., Rajagopal, A., Jones, B. V., Holland, S., & Limbrick, D. D. (2012). Longitudinal comparison of diffusion tensor imaging parameters and neuropsychological measures following endoscopic third ventriculostomy for hydrocephalus. Case report. Journal of Neurosurgery: Pediatrics, 9(6), 630-635. https://doi.org/10.3171/2012.2.PEDS11331

@article{1d5c0cca840f412e837c7b0f0a5092f1,

title = "Longitudinal comparison of diffusion tensor imaging parameters and neuropsychological measures following endoscopic third ventriculostomy for hydrocephalus. Case report",

abstract = "The authors report the case of a 25-month-old boy who underwent endoscopic third ventriculostomy (ETV) for hydrocephalus resulting from aqueductal stenosis. The patient's recovery was monitored longitudinally and prospectively using MR diffusion tensor imaging (DTI) and formal neuropsychological testing. Despite minimal change in ventricle size, improvement in the DTI characteristics and neurodevelopmental trajectory was observed following ETV. These data support the use of DTI as a biomarker to assess therapeutic response in children undergoing surgical treatment for hydrocephalus. In the patient featured in this report, DTI appeared to provide more information regarding postoperative neurodevelopmental outcome than ventricle size alone.",

keywords = "Diffusion tensor imaging, Endoscopic third ventriculostomy, Hydrocephalus, Neuropsychological outcome",

author = "Buckley, {Robert T.} and Weihong Yuan and Mangano, {Francesco T.} and Phillips, {Jannel M.} and Stephanie Powell and McKinstry, {Robert C.} and Akila Rajagopal and Jones, {Blaise V.} and Scott Holland and Limbrick, {David D.}",

year = "2012",

month = jun,

doi = "10.3171/2012.2.PEDS11331",

language = "English (US)",

volume = "9",

pages = "630--635",

journal = "Journal of Neurosurgery: Pediatrics",

issn = "1933-0707",

publisher = "American Association of Neurological Surgeons",

number = "6",

}

Buckley, RT, Yuan, W, Mangano, FT, Phillips, JM, Powell, S, McKinstry, RC, Rajagopal, A, Jones, BV, Holland, S & Limbrick, DD 2012, 'Longitudinal comparison of diffusion tensor imaging parameters and neuropsychological measures following endoscopic third ventriculostomy for hydrocephalus. Case report', Journal of Neurosurgery: Pediatrics, vol. 9, no. 6, pp. 630-635. https://doi.org/10.3171/2012.2.PEDS11331

Longitudinal comparison of diffusion tensor imaging parameters and neuropsychological measures following endoscopic third ventriculostomy for hydrocephalus. Case report. / Buckley, Robert T.; Yuan, Weihong; Mangano, Francesco T. et al.
In: Journal of Neurosurgery: Pediatrics, Vol. 9, No. 6, 06.2012, p. 630-635.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Longitudinal comparison of diffusion tensor imaging parameters and neuropsychological measures following endoscopic third ventriculostomy for hydrocephalus. Case report

AU - Buckley, Robert T.

AU - Yuan, Weihong

AU - Mangano, Francesco T.

AU - Phillips, Jannel M.

AU - Powell, Stephanie

AU - McKinstry, Robert C.

AU - Rajagopal, Akila

AU - Jones, Blaise V.

AU - Holland, Scott

AU - Limbrick, David D.

PY - 2012/6

Y1 - 2012/6

N2 - The authors report the case of a 25-month-old boy who underwent endoscopic third ventriculostomy (ETV) for hydrocephalus resulting from aqueductal stenosis. The patient's recovery was monitored longitudinally and prospectively using MR diffusion tensor imaging (DTI) and formal neuropsychological testing. Despite minimal change in ventricle size, improvement in the DTI characteristics and neurodevelopmental trajectory was observed following ETV. These data support the use of DTI as a biomarker to assess therapeutic response in children undergoing surgical treatment for hydrocephalus. In the patient featured in this report, DTI appeared to provide more information regarding postoperative neurodevelopmental outcome than ventricle size alone.

AB - The authors report the case of a 25-month-old boy who underwent endoscopic third ventriculostomy (ETV) for hydrocephalus resulting from aqueductal stenosis. The patient's recovery was monitored longitudinally and prospectively using MR diffusion tensor imaging (DTI) and formal neuropsychological testing. Despite minimal change in ventricle size, improvement in the DTI characteristics and neurodevelopmental trajectory was observed following ETV. These data support the use of DTI as a biomarker to assess therapeutic response in children undergoing surgical treatment for hydrocephalus. In the patient featured in this report, DTI appeared to provide more information regarding postoperative neurodevelopmental outcome than ventricle size alone.

KW - Diffusion tensor imaging

KW - Endoscopic third ventriculostomy

KW - Hydrocephalus

KW - Neuropsychological outcome

UR - http://www.scopus.com/inward/record.url?scp=84861813795&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861813795&partnerID=8YFLogxK

U2 - 10.3171/2012.2.PEDS11331

DO - 10.3171/2012.2.PEDS11331

M3 - Article

C2 - 22656255

AN - SCOPUS:84861813795

SN - 1933-0707

VL - 9

SP - 630

EP - 635

JO - Journal of Neurosurgery: Pediatrics

JF - Journal of Neurosurgery: Pediatrics

IS - 6

ER -

Longitudinal comparison of diffusion tensor imaging parameters and neuropsychological measures following endoscopic third ventriculostomy for hydrocephalus. Case report

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this