Longitudinal estimation of intramuscular Tibialis Anterior coherence during subacute spinal cord injury: Relationship with neurophysiological, functional and clinical outcome measures

Elisabeth Bravo-Esteban, Julian Taylor*, Manuel Aleixandre, Cristina Simón-Martínez, Diego Torricelli, Jose L Pons, Gerardo Avila-Martín, Iriana Galán-Arriero, Julio Gómez-Soriano

*Corresponding author for this work

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Background Estimation of surface intramuscular coherence has been used to indirectly assess pyramidal tract activity following spinal cord injury (SCI), especially within the 15-30 Hz bandwidth. However, change in higher frequency (>40 Hz) muscle coherence during SCI has not been characterised. Thus, the objective of this study was to identify change of high and low frequency intramuscular Tibialis Anterior (TA) coherence during incomplete subacute SCI. Methods Fifteen healthy subjects and 22 subjects with motor incomplete SCI (American Spinal Injury Association Impairment Scale, AIS, C or D grade) were recruited and tested during 4 sessions performed at 2-week intervals up to 8 months after SCI. Intramuscular TA coherence estimation was calculated within the 10-60 Hz bandwidth during controlled maximal isometric and isokinetic foot dorsiflexion. Maximal voluntary dorsiflexion torque, gait function measured with the WISCI II scale, and TA motor evoked potentials (MEP) were recorded. Results During subacute SCI, significant improvement in total lower limb manual muscle score, TA muscle strength and gait function were observed. No change in TA MEP amplitude was identified. Significant increase in TA coherence was detected in the 40-60 Hz, but not the 15-30 Hz bandwidth. The spasticity syndrome was associated with lower 15-30 Hz TA coherence during maximal isometric dorsiflexion and higher 10-60 Hz coherence during fast isokinetic movement (p < 0.05). Conclusions Longitudinal estimation of neurophysiological and clinical measures during subacute SCI suggest that estimation of TA muscle coherence during controlled movement provides indirect information regarding adaptive and maladaptive motor control mechanisms during neurorehabilitation.

Original languageEnglish (US)
Article number58
JournalJournal of neuroengineering and rehabilitation
Volume14
Issue number1
DOIs
StatePublished - 2017

Keywords

  • Motor evoked potentials
  • Motor recovery
  • Muscle coherence
  • Neuronal plasticity
  • Spinal cord injuries
  • Spinal cord injury spasticity

ASJC Scopus subject areas

  • Rehabilitation
  • Health Informatics

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