Low birth weight is associated with chronic kidney disease only in men

S. Li; S. C. Chen; M. Shlipak; G. Bakris; P. A. McCullough; J. Sowers; L. Stevens; C. Jurkovitz; S. McFarlane; K. Norris; J. Vassalotti; M. J. Klag; W. W. Brown; A. Narva; D. Calhoun; B. Johnson; C. Obialo; A. Whaley-Connell; B. Becker; A. J. Collins

doi:10.1038/sj.ki.5002747

Low birth weight is associated with chronic kidney disease only in men

S. Li, S. C. Chen, M. Shlipak, G. Bakris, P. A. McCullough, J. Sowers, L. Stevens, C. Jurkovitz, S. McFarlane, K. Norris, J. Vassalotti, M. J. Klag, W. W. Brown, A. Narva, D. Calhoun, B. Johnson, C. Obialo, A. Whaley-Connell, B. Becker, A. J. Collins^*

^*Corresponding author for this work

Medicine, Nephrology Division

Research output: Contribution to journal › Article › peer-review

100 Scopus citations

Abstract

The association of low birth weight and chronic kidney disease was examined in a screened volunteer population by the National Kidney Foundation's Kidney Early Evaluation Program. This is a free, community-based health program enrolling individuals aged 18 years or older with diabetes, hypertension, or a family history of kidney disease, diabetes, or hypertension. Self-reported birth weight was categorized and chronic kidney disease defined as an estimated glomerular filtration rate less than 60 ml per min per 1.73 m² or a urine albumin/creatinine ratio ≥30 mg/g. Among 12 364 participants, 15% reported a birth weight less than 2500 g. In men, significant corresponding odds ratios were found after adjustment for demographic characteristics and health conditions to this low birth weight and chronic kidney disease, but there was no association among women. There was no significant interaction between birth weight and race for either gender. Efforts to clinically understand the etiology of this association and potential means of prevention are essential to improving public health.

Original language	English (US)
Pages (from-to)	637-642
Number of pages	6
Journal	Kidney international
Volume	73
Issue number	5
DOIs	https://doi.org/10.1038/sj.ki.5002747
State	Published - Mar 2008

Funding

The KEEP is a program of the National Kidney Foundation Inc., and is supported by Amgen, Abbott, Genzyme, Ortho Biotech Products, LP, and Novartis. Additional support is provided by Siemens Medical Solutions Diagnostics, Lifescan, Suplena, and OceanSpray Cranberries. The authors have no conflicts of interest with the subject matter of this manuscript.

Keywords

Birth weight
Chronic kidney disease
Diabetes
Hypertension
Nephron

ASJC Scopus subject areas

Nephrology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/sj.ki.5002747

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Li, S., Chen, S. C., Shlipak, M., Bakris, G., McCullough, P. A., Sowers, J., Stevens, L., Jurkovitz, C., McFarlane, S., Norris, K., Vassalotti, J., Klag, M. J., Brown, W. W., Narva, A., Calhoun, D., Johnson, B., Obialo, C., Whaley-Connell, A., Becker, B., & Collins, A. J. (2008). Low birth weight is associated with chronic kidney disease only in men. Kidney international, 73(5), 637-642. https://doi.org/10.1038/sj.ki.5002747

@article{8ac48d14902e49d284662659c4416051,

title = "Low birth weight is associated with chronic kidney disease only in men",

abstract = "The association of low birth weight and chronic kidney disease was examined in a screened volunteer population by the National Kidney Foundation's Kidney Early Evaluation Program. This is a free, community-based health program enrolling individuals aged 18 years or older with diabetes, hypertension, or a family history of kidney disease, diabetes, or hypertension. Self-reported birth weight was categorized and chronic kidney disease defined as an estimated glomerular filtration rate less than 60 ml per min per 1.73 m2 or a urine albumin/creatinine ratio ≥30 mg/g. Among 12 364 participants, 15% reported a birth weight less than 2500 g. In men, significant corresponding odds ratios were found after adjustment for demographic characteristics and health conditions to this low birth weight and chronic kidney disease, but there was no association among women. There was no significant interaction between birth weight and race for either gender. Efforts to clinically understand the etiology of this association and potential means of prevention are essential to improving public health.",

keywords = "Birth weight, Chronic kidney disease, Diabetes, Hypertension, Nephron",

author = "S. Li and Chen, {S. C.} and M. Shlipak and G. Bakris and McCullough, {P. A.} and J. Sowers and L. Stevens and C. Jurkovitz and S. McFarlane and K. Norris and J. Vassalotti and Klag, {M. J.} and Brown, {W. W.} and A. Narva and D. Calhoun and B. Johnson and C. Obialo and A. Whaley-Connell and B. Becker and Collins, {A. J.}",

note = "Funding Information: The KEEP is a program of the National Kidney Foundation Inc., and is supported by Amgen, Abbott, Genzyme, Ortho Biotech Products, LP, and Novartis. Additional support is provided by Siemens Medical Solutions Diagnostics, Lifescan, Suplena, and OceanSpray Cranberries. The authors have no conflicts of interest with the subject matter of this manuscript. ",

year = "2008",

month = mar,

doi = "10.1038/sj.ki.5002747",

language = "English (US)",

volume = "73",

pages = "637--642",

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Li, S, Chen, SC, Shlipak, M, Bakris, G, McCullough, PA, Sowers, J, Stevens, L, Jurkovitz, C, McFarlane, S, Norris, K, Vassalotti, J, Klag, MJ, Brown, WW, Narva, A, Calhoun, D, Johnson, B, Obialo, C, Whaley-Connell, A, Becker, B & Collins, AJ 2008, 'Low birth weight is associated with chronic kidney disease only in men', Kidney international, vol. 73, no. 5, pp. 637-642. https://doi.org/10.1038/sj.ki.5002747

TY - JOUR

T1 - Low birth weight is associated with chronic kidney disease only in men

AU - Li, S.

AU - Chen, S. C.

AU - Shlipak, M.

AU - Bakris, G.

AU - McCullough, P. A.

AU - Sowers, J.

AU - Stevens, L.

AU - Jurkovitz, C.

AU - McFarlane, S.

AU - Norris, K.

AU - Vassalotti, J.

AU - Klag, M. J.

AU - Brown, W. W.

AU - Narva, A.

AU - Calhoun, D.

AU - Johnson, B.

AU - Obialo, C.

AU - Whaley-Connell, A.

AU - Becker, B.

AU - Collins, A. J.

N1 - Funding Information: The KEEP is a program of the National Kidney Foundation Inc., and is supported by Amgen, Abbott, Genzyme, Ortho Biotech Products, LP, and Novartis. Additional support is provided by Siemens Medical Solutions Diagnostics, Lifescan, Suplena, and OceanSpray Cranberries. The authors have no conflicts of interest with the subject matter of this manuscript.

PY - 2008/3

Y1 - 2008/3

N2 - The association of low birth weight and chronic kidney disease was examined in a screened volunteer population by the National Kidney Foundation's Kidney Early Evaluation Program. This is a free, community-based health program enrolling individuals aged 18 years or older with diabetes, hypertension, or a family history of kidney disease, diabetes, or hypertension. Self-reported birth weight was categorized and chronic kidney disease defined as an estimated glomerular filtration rate less than 60 ml per min per 1.73 m2 or a urine albumin/creatinine ratio ≥30 mg/g. Among 12 364 participants, 15% reported a birth weight less than 2500 g. In men, significant corresponding odds ratios were found after adjustment for demographic characteristics and health conditions to this low birth weight and chronic kidney disease, but there was no association among women. There was no significant interaction between birth weight and race for either gender. Efforts to clinically understand the etiology of this association and potential means of prevention are essential to improving public health.

AB - The association of low birth weight and chronic kidney disease was examined in a screened volunteer population by the National Kidney Foundation's Kidney Early Evaluation Program. This is a free, community-based health program enrolling individuals aged 18 years or older with diabetes, hypertension, or a family history of kidney disease, diabetes, or hypertension. Self-reported birth weight was categorized and chronic kidney disease defined as an estimated glomerular filtration rate less than 60 ml per min per 1.73 m2 or a urine albumin/creatinine ratio ≥30 mg/g. Among 12 364 participants, 15% reported a birth weight less than 2500 g. In men, significant corresponding odds ratios were found after adjustment for demographic characteristics and health conditions to this low birth weight and chronic kidney disease, but there was no association among women. There was no significant interaction between birth weight and race for either gender. Efforts to clinically understand the etiology of this association and potential means of prevention are essential to improving public health.

KW - Birth weight

KW - Chronic kidney disease

KW - Diabetes

KW - Hypertension

KW - Nephron

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C2 - 18094674

AN - SCOPUS:39349106654

SN - 0085-2538

VL - 73

SP - 637

EP - 642

JO - Kidney international

JF - Kidney international

IS - 5

ER -

Low birth weight is associated with chronic kidney disease only in men

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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Cite this