Low-Density 2D Superlattices Assembled via Directional DNA Bonding

Ziyi Miao, Cindy Y. Zheng, George C. Schatz, Byeongdu Lee, Chad A. Mirkin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


It is critical to assemble nanoparticles (NPs) into superlattices with controlled symmetries and spacings on substrates for metamaterials applications, where such structural parameters dictate their properties. Here, we use DNA to assemble anisotropic NPs of three shapes—cubes, octahedra, and rhombic dodecahedra—on substrates and investigate their thermally induced reorganization into two-dimensional (2D) crystalline films. We report two new low-density 2D structures, including a honeycomb lattice based on octahedral NPs. The low-density lattices favored here are not usually seen when particles are crystallized via other bottom-up assembly techniques. Furthermore, we show that, consistent with the complementary contact model, a primary driving force for crystallization is the formation of directional, face-to-face DNA bonds between neighboring NPs and between NPs and the substrate. Our results can be used to deliberately prepare crystalline NP films with novel morphologies.

Original languageEnglish (US)
Pages (from-to)19035-19040
Number of pages6
JournalAngewandte Chemie - International Edition
Issue number35
StatePublished - Aug 23 2021


  • DNA
  • colloidal crystals
  • nanoparticle superlattice
  • nanoparticles
  • small-angle X-ray scattering

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)


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