Low rates of heterotopic ossification after resurfacing hip arthroplasty with use of prophylactic radiotherapy in select patients

Tim J. Kruser; Kevin R. Kozak; Donald M. Cannon; Christopher S. Platta; John P. Heiner; Richard L. Illgen

doi:10.1016/j.arth.2011.11.017

Low rates of heterotopic ossification after resurfacing hip arthroplasty with use of prophylactic radiotherapy in select patients

Tim J. Kruser^*, Kevin R. Kozak, Donald M. Cannon, Christopher S. Platta, John P. Heiner, Richard L. Illgen

^*Corresponding author for this work

Radiation Oncology

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Recent reports have noted higher rates of heterotopic ossification (HO) with surface replacement arthroplasty (SRA) than with traditional total hip arthroplasty in the absence of postoperative HO prophylaxis. This study reports rates and grades of HO in 44 SRA patients with at least 1 year of follow-up. Heterotopic ossification prophylaxis was used in 32 (73%) of 44 cases. Heterotopic ossification prophylaxis consisted of radiotherapy (22/32), nonsteroidal anti-inflammatory drugs (8/32), or both (2/32). One case of clinically significant HO was documented in the no-prophylaxis group. This strategy of selective HO prophylaxis in patients felt by orthopedic surgeons to be at high risk of HO resulted in low rates of clinically relevant HO after SRA (1/44, 2.3%). Further study is needed to establish optimal selection criteria for HO prophylaxis after SRA.

Original language	English (US)
Pages (from-to)	1349-1353
Number of pages	5
Journal	Journal of Arthroplasty
Volume	27
Issue number	7
DOIs	https://doi.org/10.1016/j.arth.2011.11.017
State	Published - Aug 2012

Keywords

Heterotopic ossification
Prophylactic radiation
Surface replacement arthroplasty

ASJC Scopus subject areas

Orthopedics and Sports Medicine

Access to Document

10.1016/j.arth.2011.11.017

Cite this

@article{5ec9d56504d8486a864177f4a5920dc3,

title = "Low rates of heterotopic ossification after resurfacing hip arthroplasty with use of prophylactic radiotherapy in select patients",

abstract = "Recent reports have noted higher rates of heterotopic ossification (HO) with surface replacement arthroplasty (SRA) than with traditional total hip arthroplasty in the absence of postoperative HO prophylaxis. This study reports rates and grades of HO in 44 SRA patients with at least 1 year of follow-up. Heterotopic ossification prophylaxis was used in 32 (73%) of 44 cases. Heterotopic ossification prophylaxis consisted of radiotherapy (22/32), nonsteroidal anti-inflammatory drugs (8/32), or both (2/32). One case of clinically significant HO was documented in the no-prophylaxis group. This strategy of selective HO prophylaxis in patients felt by orthopedic surgeons to be at high risk of HO resulted in low rates of clinically relevant HO after SRA (1/44, 2.3%). Further study is needed to establish optimal selection criteria for HO prophylaxis after SRA.",

keywords = "Heterotopic ossification, Prophylactic radiation, Surface replacement arthroplasty",

author = "Kruser, {Tim J.} and Kozak, {Kevin R.} and Cannon, {Donald M.} and Platta, {Christopher S.} and Heiner, {John P.} and Illgen, {Richard L.}",

year = "2012",

month = aug,

doi = "10.1016/j.arth.2011.11.017",

language = "English (US)",

volume = "27",

pages = "1349--1353",

journal = "Journal of Arthroplasty",

issn = "0883-5403",

publisher = "Elsevier B.V.",

number = "7",

}

TY - JOUR

T1 - Low rates of heterotopic ossification after resurfacing hip arthroplasty with use of prophylactic radiotherapy in select patients

AU - Kruser, Tim J.

AU - Kozak, Kevin R.

AU - Cannon, Donald M.

AU - Platta, Christopher S.

AU - Heiner, John P.

AU - Illgen, Richard L.

PY - 2012/8

Y1 - 2012/8

N2 - Recent reports have noted higher rates of heterotopic ossification (HO) with surface replacement arthroplasty (SRA) than with traditional total hip arthroplasty in the absence of postoperative HO prophylaxis. This study reports rates and grades of HO in 44 SRA patients with at least 1 year of follow-up. Heterotopic ossification prophylaxis was used in 32 (73%) of 44 cases. Heterotopic ossification prophylaxis consisted of radiotherapy (22/32), nonsteroidal anti-inflammatory drugs (8/32), or both (2/32). One case of clinically significant HO was documented in the no-prophylaxis group. This strategy of selective HO prophylaxis in patients felt by orthopedic surgeons to be at high risk of HO resulted in low rates of clinically relevant HO after SRA (1/44, 2.3%). Further study is needed to establish optimal selection criteria for HO prophylaxis after SRA.

AB - Recent reports have noted higher rates of heterotopic ossification (HO) with surface replacement arthroplasty (SRA) than with traditional total hip arthroplasty in the absence of postoperative HO prophylaxis. This study reports rates and grades of HO in 44 SRA patients with at least 1 year of follow-up. Heterotopic ossification prophylaxis was used in 32 (73%) of 44 cases. Heterotopic ossification prophylaxis consisted of radiotherapy (22/32), nonsteroidal anti-inflammatory drugs (8/32), or both (2/32). One case of clinically significant HO was documented in the no-prophylaxis group. This strategy of selective HO prophylaxis in patients felt by orthopedic surgeons to be at high risk of HO resulted in low rates of clinically relevant HO after SRA (1/44, 2.3%). Further study is needed to establish optimal selection criteria for HO prophylaxis after SRA.

KW - Heterotopic ossification

KW - Prophylactic radiation

KW - Surface replacement arthroplasty

UR - http://www.scopus.com/inward/record.url?scp=84864008288&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84864008288&partnerID=8YFLogxK

U2 - 10.1016/j.arth.2011.11.017

DO - 10.1016/j.arth.2011.11.017

M3 - Article

C2 - 22245125

AN - SCOPUS:84864008288

SN - 0883-5403

VL - 27

SP - 1349

EP - 1353

JO - Journal of Arthroplasty

JF - Journal of Arthroplasty

IS - 7

ER -

Low rates of heterotopic ossification after resurfacing hip arthroplasty with use of prophylactic radiotherapy in select patients

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this