Lower esophageal sphincter dysfunction in esophageal atresia: Nocturnal regurgitation and aspiration pneumonia

D. W. Shermeta*, P. F. Whitington, D. S. Seto, J. Alex Haller

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

The association between lower esophageal sphincter (LES) incompetence, gastroesophageal reflux, and recurrent pneumonia in patients who have undergone successful repair of esophageal atresia (EA) and tracheoesophageal fistula is demonstrated in this study. The efficacy of esophageal manometric examination in the evaluation of the LES in young children after EA repair is documented. This study also provides evidence that infants and children with LES incompetence associated with EA may have LES responsiveness to bethanechol. Once established by manometry, this responsiveness may be used to manage the patient until surgical repair would be advantageous.

Original languageEnglish (US)
Pages (from-to)871-876
Number of pages6
JournalJournal of pediatric surgery
Volume12
Issue number6
DOIs
StatePublished - Dec 1977

Keywords

  • Esophageal atresia
  • bethanechol
  • esophageal manometry
  • gastroesophageal reflux
  • lower esophageal sphincter incompetence
  • tracheoesophageal fistula

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

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