Lower esophageal sphincter dysfunction in esophageal atresia: Nocturnal regurgitation and aspiration pneumonia

D. W. Shermeta; P. F. Whitington; D. S. Seto; J. Alex Haller

doi:10.1016/0022-3468(77)90596-6

Lower esophageal sphincter dysfunction in esophageal atresia: Nocturnal regurgitation and aspiration pneumonia

D. W. Shermeta^*, P. F. Whitington, D. S. Seto, J. Alex Haller

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

The association between lower esophageal sphincter (LES) incompetence, gastroesophageal reflux, and recurrent pneumonia in patients who have undergone successful repair of esophageal atresia (EA) and tracheoesophageal fistula is demonstrated in this study. The efficacy of esophageal manometric examination in the evaluation of the LES in young children after EA repair is documented. This study also provides evidence that infants and children with LES incompetence associated with EA may have LES responsiveness to bethanechol. Once established by manometry, this responsiveness may be used to manage the patient until surgical repair would be advantageous.

Original language	English (US)
Pages (from-to)	871-876
Number of pages	6
Journal	Journal of pediatric surgery
Volume	12
Issue number	6
DOIs	https://doi.org/10.1016/0022-3468(77)90596-6
State	Published - Dec 1977

Keywords

Esophageal atresia
bethanechol
esophageal manometry
gastroesophageal reflux
lower esophageal sphincter incompetence
tracheoesophageal fistula

ASJC Scopus subject areas

Surgery
Pediatrics, Perinatology, and Child Health

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10.1016/0022-3468(77)90596-6

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title = "Lower esophageal sphincter dysfunction in esophageal atresia: Nocturnal regurgitation and aspiration pneumonia",

abstract = "The association between lower esophageal sphincter (LES) incompetence, gastroesophageal reflux, and recurrent pneumonia in patients who have undergone successful repair of esophageal atresia (EA) and tracheoesophageal fistula is demonstrated in this study. The efficacy of esophageal manometric examination in the evaluation of the LES in young children after EA repair is documented. This study also provides evidence that infants and children with LES incompetence associated with EA may have LES responsiveness to bethanechol. Once established by manometry, this responsiveness may be used to manage the patient until surgical repair would be advantageous.",

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year = "1977",

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T2 - Nocturnal regurgitation and aspiration pneumonia

AU - Shermeta, D. W.

AU - Whitington, P. F.

AU - Seto, D. S.

AU - Haller, J. Alex

PY - 1977/12

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N2 - The association between lower esophageal sphincter (LES) incompetence, gastroesophageal reflux, and recurrent pneumonia in patients who have undergone successful repair of esophageal atresia (EA) and tracheoesophageal fistula is demonstrated in this study. The efficacy of esophageal manometric examination in the evaluation of the LES in young children after EA repair is documented. This study also provides evidence that infants and children with LES incompetence associated with EA may have LES responsiveness to bethanechol. Once established by manometry, this responsiveness may be used to manage the patient until surgical repair would be advantageous.

AB - The association between lower esophageal sphincter (LES) incompetence, gastroesophageal reflux, and recurrent pneumonia in patients who have undergone successful repair of esophageal atresia (EA) and tracheoesophageal fistula is demonstrated in this study. The efficacy of esophageal manometric examination in the evaluation of the LES in young children after EA repair is documented. This study also provides evidence that infants and children with LES incompetence associated with EA may have LES responsiveness to bethanechol. Once established by manometry, this responsiveness may be used to manage the patient until surgical repair would be advantageous.

KW - Esophageal atresia

KW - bethanechol

KW - esophageal manometry

KW - gastroesophageal reflux

KW - lower esophageal sphincter incompetence

KW - tracheoesophageal fistula

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Lower esophageal sphincter dysfunction in esophageal atresia: Nocturnal regurgitation and aspiration pneumonia

Abstract

Keywords

ASJC Scopus subject areas

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