Lower urinary tract symptoms, obesity and the metabolic syndrome

Samdeep K Mouli, Kevin T. McVary

Research output: Contribution to journalReview articlepeer-review

70 Scopus citations

Abstract

Purpose of review: The epidemic of obesity and concomitant metabolic syndrome is well documented. New evidence points to a connection between the components of metabolic syndrome and benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). Recent findings: Multiple studies have demonstrated a strong independent association between the components of metabolic syndrome and BPH/LUTS. Furthermore, modifiable risk factors, such as increased physical activity, appear to decrease the risk of BPH/LUTS. Summary: Emerging data points to a strong relationship between metabolic syndrome and BPH/LUTS, indicating a common cause. Further exploration of this relationship may result in a new understanding of the pathophysiology, treatment, and prevention of these disorders.

Original languageEnglish (US)
Pages (from-to)7-12
Number of pages6
JournalCurrent Opinion in Urology
Volume20
Issue number1
DOIs
StatePublished - Jan 1 2010

Keywords

  • Benign prostatic hyperplasia
  • C-reactive protein
  • Lower urinary tract symptoms
  • Metabolic syndrome
  • Obesity

ASJC Scopus subject areas

  • Urology

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