Lumbar dorsal root potentials elicited by stimulation of nucleus locus coeruleus

A. Vania Apkarian; Charles J. Hodge; Richard T. Stevens; Joel I. Franck

doi:10.1016/0014-4886(84)90173-0

Lumbar dorsal root potentials elicited by stimulation of nucleus locus coeruleus

A. Vania Apkarian^*, Charles J. Hodge, Richard T. Stevens, Joel I. Franck

^*Corresponding author for this work

Neuroscience

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Lumbar dorsal root potentials (DRP) were elicited by nucleus locus coeruleus (LC) stimulation in the cat. Inhibition, by LC stimulation, of dorsal horn cells responding to noxious inputs corresponded in time with the DRPs evoked by LC stimulation. Comparing cutaneous stimulation-evoked DRPs with LC stimulation-evoked DRPs and their respective effects on dorsal horn single-unit activity suggested a shared segmental underlying mechanism and the possible involvement of the coeruleospinal system with that of a diffuse noxious inhibitory suprasegmental loop.

Original language	English (US)
Pages (from-to)	202-208
Number of pages	7
Journal	Experimental Neurology
Volume	85
Issue number	1
DOIs	https://doi.org/10.1016/0014-4886(84)90173-0
State	Published - Jul 1984

ASJC Scopus subject areas

Neurology
Developmental Neuroscience

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@article{af0cdaadc39146e78287d6e2669b516f,

title = "Lumbar dorsal root potentials elicited by stimulation of nucleus locus coeruleus",

abstract = "Lumbar dorsal root potentials (DRP) were elicited by nucleus locus coeruleus (LC) stimulation in the cat. Inhibition, by LC stimulation, of dorsal horn cells responding to noxious inputs corresponded in time with the DRPs evoked by LC stimulation. Comparing cutaneous stimulation-evoked DRPs with LC stimulation-evoked DRPs and their respective effects on dorsal horn single-unit activity suggested a shared segmental underlying mechanism and the possible involvement of the coeruleospinal system with that of a diffuse noxious inhibitory suprasegmental loop.",

author = "Apkarian, {A. Vania} and Hodge, {Charles J.} and Stevens, {Richard T.} and Franck, {Joel I.}",

note = "Funding Information: Abbreviations: DRP-dorsal root potential, LC-locus coeruleus, DNIC-dil%e inhibitory control. {\textquoteright} The authors thank N. J. Horton for her expert technical assistance and P. L. Corcoran for typing the manuscript. This project was supported by a grant from the Perkins Foundation and National Institutes of Health grant NS I276 l-02. Please send reprint requests to Dr. Apkarian.",

year = "1984",

month = jul,

doi = "10.1016/0014-4886(84)90173-0",

language = "English (US)",

volume = "85",

pages = "202--208",

journal = "Experimental Neurology",

issn = "0014-4886",

publisher = "Academic Press Inc.",

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TY - JOUR

T1 - Lumbar dorsal root potentials elicited by stimulation of nucleus locus coeruleus

AU - Apkarian, A. Vania

AU - Hodge, Charles J.

AU - Stevens, Richard T.

AU - Franck, Joel I.

N1 - Funding Information: Abbreviations: DRP-dorsal root potential, LC-locus coeruleus, DNIC-dil%e inhibitory control. ’ The authors thank N. J. Horton for her expert technical assistance and P. L. Corcoran for typing the manuscript. This project was supported by a grant from the Perkins Foundation and National Institutes of Health grant NS I276 l-02. Please send reprint requests to Dr. Apkarian.

PY - 1984/7

Y1 - 1984/7

N2 - Lumbar dorsal root potentials (DRP) were elicited by nucleus locus coeruleus (LC) stimulation in the cat. Inhibition, by LC stimulation, of dorsal horn cells responding to noxious inputs corresponded in time with the DRPs evoked by LC stimulation. Comparing cutaneous stimulation-evoked DRPs with LC stimulation-evoked DRPs and their respective effects on dorsal horn single-unit activity suggested a shared segmental underlying mechanism and the possible involvement of the coeruleospinal system with that of a diffuse noxious inhibitory suprasegmental loop.

AB - Lumbar dorsal root potentials (DRP) were elicited by nucleus locus coeruleus (LC) stimulation in the cat. Inhibition, by LC stimulation, of dorsal horn cells responding to noxious inputs corresponded in time with the DRPs evoked by LC stimulation. Comparing cutaneous stimulation-evoked DRPs with LC stimulation-evoked DRPs and their respective effects on dorsal horn single-unit activity suggested a shared segmental underlying mechanism and the possible involvement of the coeruleospinal system with that of a diffuse noxious inhibitory suprasegmental loop.

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JO - Experimental Neurology

JF - Experimental Neurology

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ER -

Lumbar dorsal root potentials elicited by stimulation of nucleus locus coeruleus

Abstract

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