Lung cancer in chronic obstructive pulmonary disease: Enhancing surgical options and outcomes

Stacy Raviv, Keenan A. Hawkins, Malcolm M. DeCamp, Ravi Kalhan*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

91 Scopus citations


Patients with chronic obstructive pulmonary disease (COPD) are at increased risk for both the development of primary lung cancer, as well as poor outcome after lung cancer diagnosis and treatment. Because of existing impairments in lung function, patients with COPD often do not meet traditional criteria for tolerance of definitive surgical lung cancer therapy. Emerging information regarding the physiology of lung resection in COPD indicates that postoperative decrements in lung function may be less than anticipated by traditional prediction tools. In patients with COPD, more inclusive consideration for surgical resection with curative intent may be appropriate as limited surgical resections or nonsurgical therapeutic options provide inferior survival. Furthermore, optimizing perioperative COPD medical care according to clinical practice guidelines including smoking cessation can potentially minimize morbidity and improve functional status in this often severely impaired patient population.

Original languageEnglish (US)
Pages (from-to)1138-1146
Number of pages9
JournalAmerican journal of respiratory and critical care medicine
Issue number9
StatePublished - May 1 2011

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Pulmonary and Respiratory Medicine


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