Lung transplantation has evolved as a definitive therapy for patients with end-stage ILD that is refractory to medical therapy. Early referral of patients with ILD is important to ensure appropriate timing for transplantation. Currently, lung transplantation has been associated with improved lung function, exercise capacity, quality of life, and survival in this group of patients. Donor availability and the long-term complications of infection and rejection after transplantation limit lung transplantation, however. With continued investigation into increasing the donor pool, improving immunosuppressive strategies, determining immune tolerance, and improving surgical techniques, outcomes after lung transplantation will continue to improve.
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine