Lymphatic vasculature development

Guillermo Oliver

doi:10.1038/nri1258

Lymphatic vasculature development

Guillermo Oliver^*

^*Corresponding author for this work

Medicine, Nephrology Division

Research output: Contribution to journal › Review article › peer-review

290 Scopus citations

Abstract

Although the process of blood vasculature formation has been well documented, little is known about lymphatic vasculature development, despite its importance in normal and pathological conditions. The lack of specific lymphatic markers has hampered progress in this field. However, the recent identification of genes that participate in the formation of the lymphatic vasculature denotes the beginning of a new era in which better diagnoses and therapeutic treatment(s) of lymphatic disorders could become a reachable goal.

Original language	English (US)
Pages (from-to)	35-45
Number of pages	11
Journal	Nature Reviews Immunology
Volume	4
Issue number	1
DOIs	https://doi.org/10.1038/nri1258
State	Published - Jan 2004

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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title = "Lymphatic vasculature development",

abstract = "Although the process of blood vasculature formation has been well documented, little is known about lymphatic vasculature development, despite its importance in normal and pathological conditions. The lack of specific lymphatic markers has hampered progress in this field. However, the recent identification of genes that participate in the formation of the lymphatic vasculature denotes the beginning of a new era in which better diagnoses and therapeutic treatment(s) of lymphatic disorders could become a reachable goal.",

author = "Guillermo Oliver",

note = "Funding Information: I thank J. Wigle and N. Harvey, whose outstanding work in my laboratory has been instrumental in the progress of many of the ideas presented here, J. Morgan and S. Rockson for help with the figures, N. Harvey for critical reading of the manuscript and A. McArthur for scientific editing. This work was supported by the National Institutes of Health, Cancer Center Support from the National Cancer Institute and the American Lebanese Syrian Associated Charities (ALSAC).",

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N2 - Although the process of blood vasculature formation has been well documented, little is known about lymphatic vasculature development, despite its importance in normal and pathological conditions. The lack of specific lymphatic markers has hampered progress in this field. However, the recent identification of genes that participate in the formation of the lymphatic vasculature denotes the beginning of a new era in which better diagnoses and therapeutic treatment(s) of lymphatic disorders could become a reachable goal.

AB - Although the process of blood vasculature formation has been well documented, little is known about lymphatic vasculature development, despite its importance in normal and pathological conditions. The lack of specific lymphatic markers has hampered progress in this field. However, the recent identification of genes that participate in the formation of the lymphatic vasculature denotes the beginning of a new era in which better diagnoses and therapeutic treatment(s) of lymphatic disorders could become a reachable goal.

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Lymphatic vasculature development

Abstract

ASJC Scopus subject areas

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