Lymphatic vasculature development: Current concepts

Guillermo Oliver*, R. Sathish Srinivasan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

56 Scopus citations

Abstract

The recent identification of lymphatic endothelial cell-specific markers and the generation of mouse models harboring mutations in many genes that encode those markers have enabled us to begin to elucidate the developmental steps that go toward establishing the lymphatic vasculature network. Understanding these basic mechanisms of lymphatic development will improve our ability to diagnose, prevent, and ideally treat lymphatic disorders.

Original languageEnglish (US)
Pages (from-to)75-81
Number of pages7
JournalAnnals of the New York Academy of Sciences
Volume1131
DOIs
StatePublished - May 2008

Keywords

  • EphrinB2
  • Foxc2
  • Lymphangiogenesis
  • Podoplanin
  • Prox1

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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