Lymphocytic choriomeningitis virus: Emerging fetal teratogen

Leslie L. Barton*, Marilyn B. Mets, Cynthia L. Beauchamp

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

162 Scopus citations

Abstract

Lymphocytic choriomeningitis virus (LCMV), a rodent-borne arenavirus, is an often undiagnosed human fetal teratogen. We describe a neonate born with hydrocephalus and chorioretinitis after maternal second-trimester symptomatic LCMV infection. Previously reported affected infants are reviewed. We strongly suggest that obstetricians counsel their pregnant patients regarding the potential hazard that contact with infected pet, laboratory, and household mice and hamsters poses to pregnant women and their unborn children.

Original languageEnglish (US)
Pages (from-to)1715-1716
Number of pages2
JournalAmerican journal of obstetrics and gynecology
Volume187
Issue number6
DOIs
StatePublished - Dec 1 2002

Funding

Supported in part by a grant from the Guild Fund of the Children's Memorial Hospital (M. B. M.) and an unrestricted grant from Research to Prevent Blindness, Chicago, Ill.

Keywords

  • Congenital infection
  • Fetal teratogen
  • Lymphocytic choriomeningitis virus
  • Zoonosis

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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