TY - JOUR
T1 - M-signal hypothesis - metabolic modulation of membrane functions in rat brain
AU - Mayanil, Chandra Shekhar K
AU - Baquer, Najma Zaheer
PY - 1989
Y1 - 1989
N2 - 1. 1. Monoamine oxidase (amine: oxygen oxidoreductase [deaminating], EC 1.4.3.4) (MAO) and Na+ K+ ATPase ( Na+ K+-ATPase, Mg2+-dependent ATP phosphohydrolase, EC 3,1,6,3) showed reciprocal relationship in their activity patterns during experimentally perturbed situations in vivo as well as in vitro. 2. 2. M-signal hypothesis Is proposed, which attempts at explaining the regulation of plasma membrane function by the intermediate of metabolic processes in the cell. This metabolic intermediate referred to as M-signal exercise its influence on the plasma membrane Na+ K+ ATPase which is responsible for the uptake process.
AB - 1. 1. Monoamine oxidase (amine: oxygen oxidoreductase [deaminating], EC 1.4.3.4) (MAO) and Na+ K+ ATPase ( Na+ K+-ATPase, Mg2+-dependent ATP phosphohydrolase, EC 3,1,6,3) showed reciprocal relationship in their activity patterns during experimentally perturbed situations in vivo as well as in vitro. 2. 2. M-signal hypothesis Is proposed, which attempts at explaining the regulation of plasma membrane function by the intermediate of metabolic processes in the cell. This metabolic intermediate referred to as M-signal exercise its influence on the plasma membrane Na+ K+ ATPase which is responsible for the uptake process.
KW - catecholamine-derived aldehyde
KW - metabolism
KW - monoamine oxidase Na K ATPase
KW - plasma membrane
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U2 - 10.1016/0278-5846(89)90065-1
DO - 10.1016/0278-5846(89)90065-1
M3 - Article
C2 - 2550997
AN - SCOPUS:0024434256
VL - 13
SP - 781
EP - 784
JO - Progress in Neuro-Psychopharmacology and Biological Psychiatry
JF - Progress in Neuro-Psychopharmacology and Biological Psychiatry
SN - 0278-5846
IS - 5
ER -