Macrophage infiltration of pancreatic acini and islets in acute Kawasaki disease

Masaru Miura*, Francesca Garcia, Susan E. Crawford, Anne H. Rowley

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

A report of 2 patients who developed diabetes after Kawasaki disease (KD) led us to determine whether macrophages and/or T cells infiltrate acute KD pancreas. Three of 10 acute fatal KD cases had diffuse macrophage infiltration of the pancreas; T cells were not prominent. Affected islets were seen in close proximity to normal islets. These findings may explain the rarity of diabetes after KD.

Original languageEnglish (US)
Pages (from-to)1106-1108
Number of pages3
JournalPediatric Infectious Disease Journal
Volume22
Issue number12
DOIs
StatePublished - Dec 2003

Keywords

  • Diabetes mellitus
  • Immunohistochemistry.
  • Kawasaki disease
  • Macrophage
  • Pancreatitis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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