Abstract
The invention relates to magnetic resonance imaging agents comprising a paramagnetic metal ion bound to a complex wherein said complex comprises a chelator and a blocking moiety convalently attached to said chelator which binds in at least a first coordination site of said metal ion and which is capable of interacting with a target substance such that the exchange of water in at least said first coordination site is increased.
| Original language | English (US) |
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| Patent number | 5707605 |
| Filing date | 6/7/95 |
| State | Published - Jan 13 1998 |