Magnetic resonance imaging agents for the detection of physiological agents

Thomas J Meade (Inventor), Scott Fraser (Inventor), Russell Jacobs (Inventor)

Research output: Patent

Abstract

The invention relates to magnetic resonance imaging agents comprising a paramagnetic metal ion bound to a complex wherein said complex comprises a chelator and a blocking moiety convalently attached to said chelator which binds in at least a first coordination site of said metal ion and which is capable of interacting with a target substance such that the exchange of water in at least said first coordination site is increased.
Original languageEnglish (US)
Patent number5707605
Filing date6/7/95
StatePublished - Jan 13 1998

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