Magnetic Resonance Imaging Functional Activation of Left Frontal Cortex During Covert Word Production

L. Rueckert, I. Appollonio, J. Grafman*, P. Jezzard, R. Johnson, D. Le Bihan, R. Turner

*Corresponding author for this work

Research output: Contribution to journalArticle

106 Scopus citations

Abstract

Six normal volunteers underwent 4-T functional magnetic resonance imaging while performing a covert letter fluency task. An echo planar imaging sequence was utilized to detect activation based on deoxyhemoglobin contrast. All 6 subjects showed consistent activation in the frontal operculum and premotor and primary motor cortices. Activation was also detected in the supramarginal gyrus and the posterior part of the superior temporal gyrus. These results show that magnetic resonance functional neuroimaging can be used to investigate cerebral activity noninvasively during performance of complex cognitive tasks.

Original languageEnglish (US)
Pages (from-to)67-70
Number of pages4
JournalJournal of Neuroimaging
Volume4
Issue number2
DOIs
StatePublished - Jan 1 1994

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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