Magnetic resonance imaging versus computed tomography for identification and quantification of intraventricular hemorrhage

Anna L. Romanova, Alexander J. Nemeth, Michael D. Berman, James C. Guth, Eric M. Liotta, Andrew M. Naidech, Matthew B. Maas*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Background Intraventricular hemorrhage (IVH) may be difficult to detect especially when in small amounts and may affect outcomes. The objective of this study was to compare the sensitivity of magnetic resonance imaging (MRI) vs computed tomography (CT) for the identification and quantification of IVH.

Methods Patients with primary intracerebral hemorrhage were enrolled into a prospective registry between December 2006 and June 2013. Diagnostic and surveillance neuroimaging studies were analyzed for the presence of IVH and quantified by Graeb score. In subjects who developed IVH and underwent both MRI and CT, each MRI was paired with the CT scan done at the closest time point, and Graeb scores were compared with the Wilcoxon signed rank test for related samples.

Results There were 289 subjects in the cohort with IVH found in 171. Sixty-eight pairs of MRI and CT were available for comparison. CT failed to detect IVH in 3% of cases, whereas MRI was 100% sensitive. MRI and CT yielded equal Graeb scores in 72% of the pairs, and MRI Graeb score was higher in 24% (P =.007).

Conclusions MRI identifies small volumes of IVH in cases not detected by CT and yields higher estimates of intraventricular blood volume. These data indicate that consideration of technical differences is needed when comparing images from the 2 modalities in the evaluation for IVH.

Original languageEnglish (US)
Pages (from-to)2036-2040
Number of pages5
JournalJournal of Stroke and Cerebrovascular Diseases
Issue number8
StatePublished - Sep 1 2014


  • CT
  • MRI
  • computed tomography
  • intracerebral hemorrhage
  • intraventricular hemorrhage
  • magnetic resonance imaging

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Rehabilitation
  • Surgery


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