TY - JOUR
T1 - Magnetic resonance spectroscopy of the canine brain at 3.0T and 7.0T
AU - Martin-Vaquero, Paula
AU - da Costa, Ronaldo C.
AU - Echandi, Rita L.
AU - Sammet, Christina L.
AU - Knopp, Michael V.
AU - Sammet, Steffen
N1 - Funding Information:
Dr. Martin-Vaquero was sponsored by Obra Social “la Caixa” Fellowship Program of Spain.
PY - 2012/8
Y1 - 2012/8
N2 - The purpose of this study was to evaluate the feasibility of proton magnetic resonance spectroscopy ( 1H MRS) to study the concentration of metabolites in the brain of dogs at 3.0 and 7.0T. Four healthy male beagles were scanned using 3.0T and 7.0T human magnetic resonance imaging (MRI) units. The results obtained showed that all dogs had excellent quality spectra for a small (1cm 3) and large (8cm 3) voxel at 3.0T, whereas only 2 dogs had high quality spectra at 7.0T due to insufficient water suppression. 1H MRS at 3.0T appears to be a reliable method to study metabolite concentrations in the canine brain. The development of more advanced water suppression techniques is necessary to improve the results at 7.0T.
AB - The purpose of this study was to evaluate the feasibility of proton magnetic resonance spectroscopy ( 1H MRS) to study the concentration of metabolites in the brain of dogs at 3.0 and 7.0T. Four healthy male beagles were scanned using 3.0T and 7.0T human magnetic resonance imaging (MRI) units. The results obtained showed that all dogs had excellent quality spectra for a small (1cm 3) and large (8cm 3) voxel at 3.0T, whereas only 2 dogs had high quality spectra at 7.0T due to insufficient water suppression. 1H MRS at 3.0T appears to be a reliable method to study metabolite concentrations in the canine brain. The development of more advanced water suppression techniques is necessary to improve the results at 7.0T.
KW - Brain
KW - Dog
KW - Magnetic resonance spectroscopy
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U2 - 10.1016/j.rvsc.2011.07.025
DO - 10.1016/j.rvsc.2011.07.025
M3 - Article
C2 - 21864873
AN - SCOPUS:84861482586
SN - 0034-5288
VL - 93
SP - 427
EP - 429
JO - Research in Veterinary Science
JF - Research in Veterinary Science
IS - 1
ER -
