Making imines without making water - exploiting a recognition-mediated Aza-Wittig reaction

Vicente Del Amo*, Douglas Philp

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

(Figure Presented) A recognition-mediated aza-Wittig reaction permits the efficient formation of an imine in dry CDCl3 from an iminophosphorane and an aldehyde. The kinetic and thermodynamic parameters for this reaction are compared with those obtained from a condensation reaction between an aldehyde and an amine that forms the same product.

Original languageEnglish (US)
Pages (from-to)301-304
Number of pages4
JournalOrganic Letters
Volume11
Issue number2
DOIs
StatePublished - Jan 15 2009

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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