Making imines without making water - exploiting a recognition-mediated Aza-Wittig reaction

Vicente Del Amo; Douglas Philp

doi:10.1021/ol8024499

Making imines without making water - exploiting a recognition-mediated Aza-Wittig reaction

Vicente Del Amo^*, Douglas Philp

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

(Figure Presented) A recognition-mediated aza-Wittig reaction permits the efficient formation of an imine in dry CDCl₃ from an iminophosphorane and an aldehyde. The kinetic and thermodynamic parameters for this reaction are compared with those obtained from a condensation reaction between an aldehyde and an amine that forms the same product.

Original language	English (US)
Pages (from-to)	301-304
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	2
DOIs	https://doi.org/10.1021/ol8024499
State	Published - Jan 15 2009

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol8024499

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title = "Making imines without making water - exploiting a recognition-mediated Aza-Wittig reaction",

abstract = "(Figure Presented) A recognition-mediated aza-Wittig reaction permits the efficient formation of an imine in dry CDCl3 from an iminophosphorane and an aldehyde. The kinetic and thermodynamic parameters for this reaction are compared with those obtained from a condensation reaction between an aldehyde and an amine that forms the same product.",

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AU - Philp, Douglas

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N2 - (Figure Presented) A recognition-mediated aza-Wittig reaction permits the efficient formation of an imine in dry CDCl3 from an iminophosphorane and an aldehyde. The kinetic and thermodynamic parameters for this reaction are compared with those obtained from a condensation reaction between an aldehyde and an amine that forms the same product.

AB - (Figure Presented) A recognition-mediated aza-Wittig reaction permits the efficient formation of an imine in dry CDCl3 from an iminophosphorane and an aldehyde. The kinetic and thermodynamic parameters for this reaction are compared with those obtained from a condensation reaction between an aldehyde and an amine that forms the same product.

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Making imines without making water - exploiting a recognition-mediated Aza-Wittig reaction

Abstract

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