Male genital lymphedema: clinical features and management in 25 pediatric patients

Carolyn C. Schook, Ann M. Kulungowski, Arin K. Greene, Steven J. Fishman

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

PURPOSE: Genital lymphedema in the pediatric population is poorly understood. The purpose of this study was to determine the epidemiology, morbidity, and treatment outcomes for males with genital lymphedema.

MATERIALS AND METHODS: Male patients with genital lymphedema evaluated at our vascular anomalies center between 1995 and 2011 were reviewed. Etiology, age-of-onset, location, morbidity, and treatment were analyzed.

RESULTS: Of the 3889 patients with vascular anomalies, 25 (0.6%) had genital lymphedema: 92% (23/25) with primary and 24.0% (6/25) with familial/syndromic lymphedema. For primary disease, the mean age-of-onset was 4.5 ± 6.3 years with 60.9% (14/23) presenting in infancy, 13.0% (3/23) in childhood, and 26.1% (6/23) in adolescence. Combined penoscrotal lymphedema was identified in 72.0% (18/25) of patients; 19 children (76.0%) had concomitant lower extremity involvement. The most common complication was cellulitis (24.0%). Surgical contouring was performed in 44.0% (11/25) of patients. Patients with operative intervention and follow-up (n=6) had sustained improvement after a median of 4.2 years (range: 0.3-11.0).

CONCLUSIONS: Lymphedema of the male genitalia is typically idiopathic. Most patients develop swelling in infancy but can present in adolescence and occasionally childhood. The penis and scrotum are usually both involved and concurrent lower-extremity swelling is common. Surgical debulking can improve symptoms and appearance.

Original languageEnglish (US)
Pages (from-to)1647-1651
Number of pages5
JournalJournal of Pediatric Surgery
Volume49
Issue number11
DOIs
StatePublished - Nov 1 2014

Fingerprint

Lymphedema
Pediatrics
Age of Onset
Blood Vessels
Lower Extremity
Male Genitalia
Morbidity
Scrotum
Cellulitis
Penis
Epidemiology
Population

Keywords

  • Genital
  • Lymphatic malformation
  • Lymphedema
  • Swelling
  • Vascular anomaly

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Schook, Carolyn C. ; Kulungowski, Ann M. ; Greene, Arin K. ; Fishman, Steven J. / Male genital lymphedema : clinical features and management in 25 pediatric patients. In: Journal of Pediatric Surgery. 2014 ; Vol. 49, No. 11. pp. 1647-1651.
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abstract = "PURPOSE: Genital lymphedema in the pediatric population is poorly understood. The purpose of this study was to determine the epidemiology, morbidity, and treatment outcomes for males with genital lymphedema.MATERIALS AND METHODS: Male patients with genital lymphedema evaluated at our vascular anomalies center between 1995 and 2011 were reviewed. Etiology, age-of-onset, location, morbidity, and treatment were analyzed.RESULTS: Of the 3889 patients with vascular anomalies, 25 (0.6{\%}) had genital lymphedema: 92{\%} (23/25) with primary and 24.0{\%} (6/25) with familial/syndromic lymphedema. For primary disease, the mean age-of-onset was 4.5 ± 6.3 years with 60.9{\%} (14/23) presenting in infancy, 13.0{\%} (3/23) in childhood, and 26.1{\%} (6/23) in adolescence. Combined penoscrotal lymphedema was identified in 72.0{\%} (18/25) of patients; 19 children (76.0{\%}) had concomitant lower extremity involvement. The most common complication was cellulitis (24.0{\%}). Surgical contouring was performed in 44.0{\%} (11/25) of patients. Patients with operative intervention and follow-up (n=6) had sustained improvement after a median of 4.2 years (range: 0.3-11.0).CONCLUSIONS: Lymphedema of the male genitalia is typically idiopathic. Most patients develop swelling in infancy but can present in adolescence and occasionally childhood. The penis and scrotum are usually both involved and concurrent lower-extremity swelling is common. Surgical debulking can improve symptoms and appearance.",
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Male genital lymphedema : clinical features and management in 25 pediatric patients. / Schook, Carolyn C.; Kulungowski, Ann M.; Greene, Arin K.; Fishman, Steven J.

In: Journal of Pediatric Surgery, Vol. 49, No. 11, 01.11.2014, p. 1647-1651.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Male genital lymphedema

T2 - clinical features and management in 25 pediatric patients

AU - Schook, Carolyn C.

AU - Kulungowski, Ann M.

AU - Greene, Arin K.

AU - Fishman, Steven J.

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N2 - PURPOSE: Genital lymphedema in the pediatric population is poorly understood. The purpose of this study was to determine the epidemiology, morbidity, and treatment outcomes for males with genital lymphedema.MATERIALS AND METHODS: Male patients with genital lymphedema evaluated at our vascular anomalies center between 1995 and 2011 were reviewed. Etiology, age-of-onset, location, morbidity, and treatment were analyzed.RESULTS: Of the 3889 patients with vascular anomalies, 25 (0.6%) had genital lymphedema: 92% (23/25) with primary and 24.0% (6/25) with familial/syndromic lymphedema. For primary disease, the mean age-of-onset was 4.5 ± 6.3 years with 60.9% (14/23) presenting in infancy, 13.0% (3/23) in childhood, and 26.1% (6/23) in adolescence. Combined penoscrotal lymphedema was identified in 72.0% (18/25) of patients; 19 children (76.0%) had concomitant lower extremity involvement. The most common complication was cellulitis (24.0%). Surgical contouring was performed in 44.0% (11/25) of patients. Patients with operative intervention and follow-up (n=6) had sustained improvement after a median of 4.2 years (range: 0.3-11.0).CONCLUSIONS: Lymphedema of the male genitalia is typically idiopathic. Most patients develop swelling in infancy but can present in adolescence and occasionally childhood. The penis and scrotum are usually both involved and concurrent lower-extremity swelling is common. Surgical debulking can improve symptoms and appearance.

AB - PURPOSE: Genital lymphedema in the pediatric population is poorly understood. The purpose of this study was to determine the epidemiology, morbidity, and treatment outcomes for males with genital lymphedema.MATERIALS AND METHODS: Male patients with genital lymphedema evaluated at our vascular anomalies center between 1995 and 2011 were reviewed. Etiology, age-of-onset, location, morbidity, and treatment were analyzed.RESULTS: Of the 3889 patients with vascular anomalies, 25 (0.6%) had genital lymphedema: 92% (23/25) with primary and 24.0% (6/25) with familial/syndromic lymphedema. For primary disease, the mean age-of-onset was 4.5 ± 6.3 years with 60.9% (14/23) presenting in infancy, 13.0% (3/23) in childhood, and 26.1% (6/23) in adolescence. Combined penoscrotal lymphedema was identified in 72.0% (18/25) of patients; 19 children (76.0%) had concomitant lower extremity involvement. The most common complication was cellulitis (24.0%). Surgical contouring was performed in 44.0% (11/25) of patients. Patients with operative intervention and follow-up (n=6) had sustained improvement after a median of 4.2 years (range: 0.3-11.0).CONCLUSIONS: Lymphedema of the male genitalia is typically idiopathic. Most patients develop swelling in infancy but can present in adolescence and occasionally childhood. The penis and scrotum are usually both involved and concurrent lower-extremity swelling is common. Surgical debulking can improve symptoms and appearance.

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KW - Swelling

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