Malignant peripheral nerve sheath tumors of the spine: A SEER database analysis

James A. Stadler; Usama Qadri; Jessica A. Tang; Justin K. Scheer; Stephanie C. Melkonian; Zachary A. Smith; Sandi K. Lam

doi:10.1016/j.jocn.2014.01.003

Malignant peripheral nerve sheath tumors of the spine: A SEER database analysis

James A. Stadler, Usama Qadri, Jessica A. Tang, Justin K. Scheer, Stephanie C. Melkonian, Zachary A. Smith, Sandi K. Lam^*

^*Corresponding author for this work

Neurological Surgery

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Peripheral nerve sheath tumors are uncommon neoplasms that can affect any area of the body. Spinal lesions, especially those that are malignant, pose difficult management challenges, and data regarding these lesions are limited by the disease rarity. This study provides a population-based analysis using the Surveillance, Epidemiology, and End Results (SEER) database, focusing on patient characteristics and treatments. Surgery is associated with improved survival, whereas radiation therapy is associated with decreased survival in this cohort with malignant peripheral nerve sheath tumor in the spine.

Original language	English (US)
Pages (from-to)	1106-1111
Number of pages	6
Journal	Journal of Clinical Neuroscience
Volume	21
Issue number	7
DOIs	https://doi.org/10.1016/j.jocn.2014.01.003
State	Published - Jul 2014

Keywords

MPNST
Peripheral nerve sheath tumor
Radiation therapy
SEER database
Spine surgery

ASJC Scopus subject areas

Clinical Neurology
Neurology
Physiology (medical)
Surgery

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jocn.2014.01.003

Cite this

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title = "Malignant peripheral nerve sheath tumors of the spine: A SEER database analysis",

abstract = "Peripheral nerve sheath tumors are uncommon neoplasms that can affect any area of the body. Spinal lesions, especially those that are malignant, pose difficult management challenges, and data regarding these lesions are limited by the disease rarity. This study provides a population-based analysis using the Surveillance, Epidemiology, and End Results (SEER) database, focusing on patient characteristics and treatments. Surgery is associated with improved survival, whereas radiation therapy is associated with decreased survival in this cohort with malignant peripheral nerve sheath tumor in the spine.",

keywords = "MPNST, Peripheral nerve sheath tumor, Radiation therapy, SEER database, Spine surgery",

author = "Stadler, {James A.} and Usama Qadri and Tang, {Jessica A.} and Scheer, {Justin K.} and Melkonian, {Stephanie C.} and Smith, {Zachary A.} and Lam, {Sandi K.}",

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TY - JOUR

T1 - Malignant peripheral nerve sheath tumors of the spine

T2 - A SEER database analysis

AU - Stadler, James A.

AU - Qadri, Usama

AU - Tang, Jessica A.

AU - Scheer, Justin K.

AU - Melkonian, Stephanie C.

AU - Smith, Zachary A.

AU - Lam, Sandi K.

PY - 2014/7

Y1 - 2014/7

N2 - Peripheral nerve sheath tumors are uncommon neoplasms that can affect any area of the body. Spinal lesions, especially those that are malignant, pose difficult management challenges, and data regarding these lesions are limited by the disease rarity. This study provides a population-based analysis using the Surveillance, Epidemiology, and End Results (SEER) database, focusing on patient characteristics and treatments. Surgery is associated with improved survival, whereas radiation therapy is associated with decreased survival in this cohort with malignant peripheral nerve sheath tumor in the spine.

AB - Peripheral nerve sheath tumors are uncommon neoplasms that can affect any area of the body. Spinal lesions, especially those that are malignant, pose difficult management challenges, and data regarding these lesions are limited by the disease rarity. This study provides a population-based analysis using the Surveillance, Epidemiology, and End Results (SEER) database, focusing on patient characteristics and treatments. Surgery is associated with improved survival, whereas radiation therapy is associated with decreased survival in this cohort with malignant peripheral nerve sheath tumor in the spine.

KW - MPNST

KW - Peripheral nerve sheath tumor

KW - Radiation therapy

KW - SEER database

KW - Spine surgery

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M3 - Article

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VL - 21

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JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

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ER -

Malignant peripheral nerve sheath tumors of the spine: A SEER database analysis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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