Management of Advanced-Stage Operable Esophageal Cancer

Ankit Bharat, Traves Crabtree*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


The incidence of esophageal cancer is increasing in the developed world, with a relative increase in adenocarcinoma compared with squamous cell carcinoma. The distensible nature of the esophagus results in delayed development of symptoms associated with esophageal cancer; hence many patients have locally advanced or metastatic cancer at the time of initial presentation. Although resection remains the treatment of choice for early-stage esophageal cancer, the best treatment strategy for locally advanced esophageal cancer is debatable and, consequently, varies at different centers. This article discusses the published literature on various available therapeutic options for the treatment of locally advanced esophageal cancer.

Original languageEnglish (US)
Pages (from-to)1179-1197
Number of pages19
JournalSurgical Clinics of North America
Issue number5
StatePublished - Oct 2012


  • Esophageal cancer
  • Neoadjuvant therapy
  • Surgery

ASJC Scopus subject areas

  • Surgery


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