Management of eyes with both idiopathic macular hole and choroidal neovascularization

Sarah H. Elsing, Eric A. Postel, Manjot K Gill, Lee Merrill Jampol, Glenn J. Jaffe*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Purpose: To describe the characteristics, treatment, and outcome of five eyes with both choroidal neovascularization (CNV) and macular hole. Methods: Medical records of five patients with both macular hole and CNV were reviewed. Results: All eyes had full-thickness macular holes. Most eyes had atypical-appearing macular holes (subretinal hemorrhage, prominent subretinal fluid, or discoloration at the hole margin) at presentation or subsequently when CNV developed. Fluorescein angiography (FA) confirmed the presence of CNV in each eye. Three eyes underwent combined macular hole repair and CNV removal, and sustained closure of these macular holes was achieved. A fourth eye underwent successful argon laser photocoagulation of extrafoveal CNV, and macular hole surgery was declined. The final eye underwent two macular hole repairs before sustained closure was achieved. Final visual acuity, ranging from 20/100 to hand motions, was limited by macular pathology and/or cataract. Conclusions: Choroidal neovascularization can occur in association with a macular hole. In eyes with an atypical-appearing macular hole, FA should be obtained to detect CNV. Excision of the CNV can be done safely in conjunction with macular hole surgery. Final visual acuity may be limited by cumulative retinal and retinal pigment epithelium damage, especially in eyes with underlying macular disease.

Original languageEnglish (US)
Pages (from-to)613-618
Number of pages6
Issue number6
StatePublished - Jan 1 2001


  • Age-related macular degeneration
  • Bruch's membrane
  • Choroidal neovascularization
  • Fluorescein angiography
  • Macular hole
  • Multifocal choroiditis and panuveitis
  • Retinal contusion
  • Retinal pigment epithelium
  • Submacular surgery

ASJC Scopus subject areas

  • Ophthalmology


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