Abstract
Diabetes is one of the world's fastest growing health challenges. Insulin therapy remains a useful regimen for many elderly patients, such as those with moderate to severe hyperglycemia, type 1 diabetes, hyperglycemic emergencies, and those who fail to maintain glucose control on non-insulin agents alone. Recent clinical trials have shown that several non-insulin agents as monotherapy, or in combination with low doses of basal insulin, have comparable efficacy and potential safety advantages to complex insulin therapy regimens. Determining the most appropriate diabetes management plan for older hospitalized patients requires consideration of many factors to prevent poor outcomes related to dysglycemia.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 491-511 |
| Number of pages | 21 |
| Journal | Clinics in Geriatric Medicine |
| Volume | 36 |
| Issue number | 3 |
| DOIs | |
| State | Published - Aug 2020 |
Funding
Funding: F.J. Pasquel and G.E. Umpierrez are partially supported by NIH grants (1K23GM128221-01A1 [F.J. Pasquel], UL1TR002378 and 1P30DK111024-01 [G.E. Umpierrez]).F.J. Pasquel has received consulting fees and research support from Merck and Dexcom, and consulting fees from Sanofi, Boehringer Ingelheim, Lilly, and AstraZeneca. G.E. Umpierrez has received unrestricted research support for inpatient studies (to Emory University) from Sanofi, Novo Nordisk, and Dexcom. A. Wallia has received research support from United Health Group, Eli Lilly, and Novo Nordisk. G.M. Davis and K. DeCarlo report no conflicts of interest. Funding: F.J. Pasquel and G.E. Umpierrez are partially supported by NIH grants ( 1K23GM128221-01A1 [F.J. Pasquel], UL1TR002378 and 1P30DK111024-01 [G.E. Umpierrez]).
Keywords
- Diabetes
- Elderly
- Hospitalized
- Hyperglycemia
- Incretin
- Inpatient
- Insulin
- Older adults
ASJC Scopus subject areas
- Geriatrics and Gerontology
