Management of newly diagnosed glioblastoma: Guidelines development, value and application

Jeffrey J. Olson*, Camilo E. Fadul, Daniel J. Brat, Srinivasan Mukundan, Timothy C. Ryken

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

40 Scopus citations

Abstract

The movement to create guidelines for management of medical maladies has been gaining strength for quality, academic, financial and political purposes over the past two decades. This applies to neurological diseases, too. Evidence-based guidelines created in a multidisciplinary fashion using predetermined criteria for grading scientific data and translating this to similarly ranked recommendations is a valuable approach to meeting this goal. The following is a summary of the methods used for, and the results of, an evidence-based guideline for the management of newly diagnosed glioblastoma. In addition to outlining recommendations by discipline, it also addresses how concerns and conflicts were addressed in their development and provides comment on future directions in management of this situation that may improve outcome. It is important that clinicians directly experienced in patient management take the lead in creation of guidelines related to the diseases they deal with, as these clinicians are clearly the most suited to being able to arrive at a meaningful and useful product.

Original languageEnglish (US)
Pages (from-to)1-23
Number of pages23
JournalJournal of Neuro-Oncology
Volume93
Issue number1
DOIs
StatePublished - 2009

Keywords

  • Chemotherapy
  • Glioblastoma
  • Guidelines
  • Neuropathology
  • Neuroradiology
  • Neurosurgery
  • Radiation Therapy

ASJC Scopus subject areas

  • Clinical Neurology
  • Cancer Research
  • Oncology
  • Neurology

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