Management of prolactinomas

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations


Prolactinomas are the most common of the hormone-secreting pituitary tumors and must be distinguished from nonsecreting tumors causing hyperprolactinemia by hypothalamic or stalk dysfunction. For both micro- and macroadenomas, dopamine agonists appear to be the treatment of choice, transsphenoidal surgery being reserved for nonresponders. For women desiring pregnancy, dopamine agonists are safe when there is a microadenoma or an intrasellar macroadenoma. However, in women with large macroadenomas desiring pregnancy, limited transsphenoidal decompression followed by bromocriptine appears to be the safest mode of treatment.

Original languageEnglish (US)
Pages (from-to)225-232
Number of pages8
JournalAnnual review of medicine
StatePublished - 1989

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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