Management of Pulmonary Complications in Neuromuscular Disease

Lisa F. Wolfe, Nanette C. Joyce*, Craig M. McDonald, Joshua O. Benditt, Jonathan Finder

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Restrictive lung disease occurs commonly in patients with neuromuscular disease. The earliest sign of respiratory compromise in the patient with neuromuscular disease is nocturnal hypoventilation, which progresses over time to include daytime hypoventilation and eventually the need for full-time mechanical ventilation. Pulmonary function testing should be done during regular follow-up visits to identify the need for assistive respiratory equipment and initiate early noninvasive ventilation. Initiation of noninvasive ventilation can improve quality of life and prolong survival in patients with neuromuscular disease.

Original languageEnglish (US)
Pages (from-to)829-853
Number of pages25
JournalPhysical Medicine and Rehabilitation Clinics of North America
Issue number4
StatePublished - Nov 1 2012


  • Nocturnal hypoventilation
  • Noninvasive ventilation
  • Pulmonary function test
  • Respiratory failure
  • Restrictive lung disease

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation


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