Management of rhinosinusitis: An evidence based approach

Andrew J. Para, Elisabeth Clayton, Anju T. Peters*

*Corresponding author for this work

Research output: Contribution to journalReview article

4 Scopus citations


Purpose of review The most recent recommendations for the management of both acute (ARS) and chronic rhinosinusitis (CRS) based on the strongest data available for each treatment modality are summarized in this review. The clinical relationships between CRS and its comorbidities are also discussed. Recent findings The most promising advances in rhinosinusitis management involve the use of mAbs (anti-IgE, anti-IL-5, anti-IL-4Rα) in trials of CRS with nasal polyposis. Otherwise, the mainstays of treatment for both ARS and CRS have largely remained the same over the past several years. Summary The treatment of ARS primarily involves symptomatic control with intranasal corticosteroids and nasal saline irrigation; antibiotics should be reserved for the patients who are believed to have bacterial rhinosinusitis. Treating CRS effectively involves using intranasal corticosteroids and irrigation, systemic corticosteroids, and potentially systemic antibiotics. Biologics (mAbs) have shown benefit in clinical studies. Providers should also be aware of concomitant disease processes that may afflict patients with CRS.

Original languageEnglish (US)
Pages (from-to)383-389
Number of pages7
JournalCurrent Opinion in Allergy and Clinical Immunology
Issue number4
StatePublished - Aug 1 2016


  • acute rhinosinusitis
  • biologic therapy
  • chronic rhinosinusitis with nasal polyps
  • chronic rhinosinusitis without nasal polyps
  • immunotherapy
  • intranasal corticosteroids
  • monoclonal antibody

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Fingerprint Dive into the research topics of 'Management of rhinosinusitis: An evidence based approach'. Together they form a unique fingerprint.

  • Cite this